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Description
K9 Advantix II Flea, Tick & Mosquito Treatment & Prevention for Large DogsK9 Advantix II Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult
K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II treatment & prevention protects dogs from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Large
Pet Lifestage
- 7 weeks and older
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.1 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 5
Works when working outside and heavy activities
Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
I use it as an Amazon delivery driver, and it works in the heat and sweat is no issue it does last for 2 hours. Reapplying it is extremely easy, no burns or sun damage to my skin. I can tell you it works cause I’m recovering from skin cancer and it works no problems or anything.
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Reviewed in the United States on May 19, 2026
★★★★★ 3
Just ok - too thick to apply evenly
Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
Just ok - very thick, so difficult to apply evenly. I use this for outdoor cycling and it works, but it's so thick that it tends to clump instead of smoothly covering the skin.
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Reviewed in the United States on April 16, 2026
★★★★★ 5
Favorite sunscreen
Style: SPF 50, Size: 8 Fl Oz (Pack of 1)
Doesn't go on greasy. Doesn't stink. Don't get sunburnt wearing it.
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Reviewed in the United States on May 6, 2026
★★★★★ 5
Excellent mineral sunscreen for sensitive skin.
Size: 3 Fl Oz (Pack of 1), Set name: Tube - 3 oz.
I’ve been using the Blue Lizard Sensitive Mineral Sunscreen, and it’s become a staple in my routine. As someone with sensitive skin, I really appreciate that it’s fragrance-free and uses zinc oxide, providing great protection without causing any irritation or breakouts. It goes on smoothly, isn't overly greasy, and the water resistance holds up well for outdoor activities. The smart cap technology is a nice touch, too. Highly recommended if you’re looking for effective, non-irritating sun protection.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
No chemicals that will be harmful!
Size: 5 Fl Oz (Pack of 2), Set name: Tube - 5 oz. 2-Pack
Ordered this mineral sunscreen looking for something simple and effective, and it’s been a solid option so far.
The zinc oxide formula is the main reason I went with it. It doesn’t rely on the same chemical ingredients found in a lot of other sunscreens, which is a big plus if you’re trying to avoid that. It feels like a cleaner option overall.
Coverage is good. It spreads evenly and holds up well, even with some water exposure. I’ve used it outdoors for extended periods, and it does its job without needing constant reapplication.
It does leave a slight white cast at first, which is pretty typical with mineral sunscreens, but it fades in as you rub it in. Not completely invisible, but manageable.
After a few uses, what stood out most is that it doesn’t have a strong smell and doesn’t irritate the skin. It just works without a lot of extras.
Compared to standard chemical sunscreens, this feels more straightforward and less harsh, especially for regular use.
For the price, it’s a great value. You’re getting strong sun protection without the added ingredients some people try to avoid.
If you’re looking for a mineral-based sunscreen that’s effective and a bit cleaner in formulation, this is a solid choice.
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Reviewed in the United States on April 19, 2026