SKU: 60270316870

AOD-9604

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Description

AOD-9604What is AOD 9604? AOD 9604 (Advanced Obesity Drug) was developed in the 1990s by Professor Frank Ng at Monash University in Australia. Its purpose was to create an anti obesity drug with the fat burning benefits of human growth hormone (HGH) but without the muscle building effects. BIOV8 uses only premium pharmaceutical grade ingredients in all of our products. Please refer to the clinical studies and research below for more details. Snapshot AOD 9604

What is AOD-9604?

AOD-9604 (Advanced Obesity Drug) was developed in the 1990s by Professor Frank Ng at Monash University in Australia. Its purpose was to create an anti-obesity drug with the fat-burning benefits of human growth hormone (HGH) but without the muscle-building effects.

BIOV8 uses only premium pharmaceutical-grade ingredients in all of our products. Please refer to the clinical studies and research below for more details.

Snapshot

AOD-9604 is considered one of the most potent weight loss peptides. According to clinical studies, it helps regulate metabolism by stimulating the body’s natural fat-burning process. AOD-9604 triggers the release of fat from obese fat cells while also limiting the formation of new fat in surrounding cells. It mimics the way natural growth hormone regulates fat metabolism without affecting blood sugar. AOD-9604 stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the process of converting food into fat).

Research conducted at Monash University revealed that AOD-9604's fat-reducing effects are controlled by a small region of the Growth Hormone molecule, which stimulates fat breakdown. It is widely regarded as a powerful weight loss peptide with minimal side effects.

While these studies are promising, they remain preliminary and further research is needed to confirm these findings. Additionally, AOD-9604 is being tested for its potential use in treating osteoarthritis, hypercholesterolemia, and supporting bone and cartilage repair. It has an excellent safety profile and has recently achieved Human GRAS (Generally Recognized As Safe) status in the USA.

Potential Benefits
  • Targets and reduces stubborn body fat
  • Triggers fat release from obese fat cells without affecting lean tissue
  • Increases IGF-1 levels, supporting fat reduction
  • Promotes energy expenditure
  • Improves lipid profiles and lipolytic activity
Key Effects
  • Mimics the body’s natural growth hormone activity
  • No adverse effects on blood sugar or body growth
  • Stimulates lipolysis (fat breakdown)
  • Inhibits lipogenesis (conversion of food into fat)

AOD-9604 does not increase appetite or raise cortisol levels, unlike the GHRP family (GHRP-6, GHRP-2, or Hexarelin).

How It Works

AOD-9604 promotes weight loss through a mechanism similar to growth hormone supplementation, but without increasing food consumption, blood sugar, or insulin resistance. It stimulates fat breakdown (lipolysis) and fat burning (oxidation) by a unique mechanism that does not require the HGH receptor.

One theory suggests that AOD-9604 interacts with a specific receptor on fat cells, triggering fat release from obese fat cells more effectively than from lean cells. This process helps reduce the accumulation of fat and boosts fat burning, particularly in visceral fat stores, which are harmful abdominal fats surrounding vital organs.

Possible Side Effects
  • Headache
  • Diarrhoea
  • Nausea
Purity, Content, and Dosage

Purity: >98% (HPLC on request)

Content: 1200mcg/ml subcutaneous injectable in a 5ml vial.

Suggested Dosage: Inject 0.25ml subcutaneously in the morning daily, followed by a cardio session. A cycle lasts up to 40 days.

Transdermal Option: 300mcg/mL x 50mL. Apply 1mL daily for 40 days.

Technical Overview and History

AOD-9604 is a modified peptide fragment of HGH, also known as GH Frag 176-191. It was developed by Professor Frank Ng at Monash University in the 1990s as a fat-burning alternative to HGH, without the muscle-building effects.

Molecular Formula: C78H123N23O23S2

Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH

Molecular Weight: 1815.08

Clinical Studies and Research

Safety and Tolerability of AOD-9604 in Humans (Heike Stier, Evert Vos, David Kenley)

Background: AOD-9604 is a safe peptide fragment of the C-terminus of HGH with activity related to weight loss. This study reviews the safety data obtained from clinical trials involving AOD-9604.

Methods: Six randomized, double-blind, placebo-controlled trials were conducted to assess the effects of AOD-9604 and whether it caused the typical side effects seen with HGH treatments, such as increased IGF-1 levels, insulin resistance, and impaired glucose tolerance.

Results: AOD-9604 did not affect serum IGF-1 levels or carbohydrate metabolism. No serious adverse events were reported, and patients did not develop anti-AOD-9604 antibodies.

Conclusion: AOD-9604 demonstrated excellent safety and tolerability, without the negative effects often seen with full-length HGH treatments.

Additional Studies:

  • Obesity drugs in clinical development. Halford JC. Curr Opin Investig Drugs. 2006 Apr;7(4):312-8.
  • The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism in obese mice. Heffernan M, Summers RJ, et al. Endocrinology. 2001 Dec;142(12):5182-9.
  • Metabolic studies of AOD9604. Ng FM, et al. Horm Res. 2000;53(6):274-8.
Beware of Counterfeit

The internet is full of counterfeit peptides and inferior products. BIOV8 is committed to providing only the highest quality pharmaceutical-grade products and can provide proof of purity and sterility. BIOV8 peptides are prescribed only by our qualified licensed practitioners, as required by law.

Please Note

* Orders of more than 2 vials of AOD will be shipped in separate packages to allow for a treatment break.

All injectables come with the necessary sharps and swabs for the duration of your treatment. We recommend purchasing a sharps disposal box for safe disposal of needles.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 60270316870

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PC
Lowell, US
★★★★★ 3
Less flavor than the pops. Very disappointing.
I bought these after trying the lollipop type of the same brand. Honestly? I was disappointed in the lack of flavor in yhe drops versus the lollipop style. The reason I purchased the drops was because I do not like dealing with the stick of the pop and just wanted the sucker part of the candy. I thought being the same flavors that they would have the same taste. They do not. The drops have much less enjoyable flavor and are quite bland in comparison to the lollipop style. I guess I'm sticking with dealing with the stick to get any good flavor. I also wish the variety of the flavors in both the Zollipops and Zolli Drops was more evenly distributed. The orange are my favorite flavor and the ratio is low compared to the pink or purple and less flavorful pieces. Anyway, just my 2 cents on the difference I noticed between the two variations of the same product.
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Reviewed in the United States on May 23, 2026
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O'bie
Whiting, US
★★★★★ 5
Drops are easier to open
I like the zolli drops better than the pops. They are easier to open!
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Reviewed in the United States on May 25, 2026
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Barefoot in the Meadow
Lowell, US
★★★★★ 5
Delicious!
Perfect for those days when you need a little something. You will never know they're sugar free, amd the flavors are on point. These are in regular rotation in our home now - and guilt free!
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Reviewed in the United States on June 10, 2025
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Lake Worth, US
★★★★★ 5
Great option for fluoride-free families, has helped my sensitive teeth dramatically
This is a great non-fluoride toothpaste. Our whole family switched to nano hydroxyapatite instead of fluoride pastes, we have had great dental visits and no regrets. No one has had a cavity since switching 2 years ago, but three of the four of us didn’t have cavities to begin with. I would say that my own sensitivity to cold (something I’ve had for 40 years) has decreased significantly since using this daily. This paste is far more effective for sensitivity than high fluoride options have been for me. My two teenage boys both love this toothpaste. My teeth feel clean. I wouldn’t say the toothpaste whitens better than any other paste does. My mouth feels fresh after brushing. I like the idea of remineralizing tooth surfaces but I don’t know how I would quantify that. The flavors are all good, I would rank them as follows: lemon lavender, mint, cinnamon mint, cardamom, ginger (don’t get it if you don’t LOVE ginger). Cardamom is really nice but I could see getting tired of it. Ginger is kinda weird. My boys love the lemon lavender the best. The flavors can be intense but in a natural, not artificial way. It’s not too sweet at all like some pastes can be. This toothpaste is absolutely worth the higher price point. I feel good about my family using it.
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Reviewed in the United States on March 11, 2026
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Jess
Pawtucket, US
★★★★★ 5
Lovely
Size: 4 Fl Oz (Pack of 1), Set name: A. Charcoal Yuzu Mint
Not one of the best flavors out there. I'm not used to charcoal. The flavor and texture is a bit off for me, makes me gag every-time but it is One of my favorite toothpastes after transition from sensodyne & proenamel. I never thought I would be able to go to a different toothpaste with my teeth being insanely sensitive. After doing some research and a family never recommend the brand boka I decided to give it a try. Let me tell you that my teeth have never felt better with the sensitivity and cleanness. It freshened your breather well and all the ingredients are so clean and good. I love that I can even give it to my toddler and not worry about her swallowing to much. Give this toothpaste a go!!!! The flavors are amazing. We have definitely tried almost all, we do end up going back to this one and the whitening one.
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Reviewed in the United States on February 28, 2026

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