PressureGuard Protocol Alternating Pressure Low Air Loss Mattress System

Call 866-218-0902 to speak with a mattress specialist.

Premium clinical therapy with powered flotation — built for patients where standard systems are not enough — alternating pressure, low air loss, and powered flotation combine in one advanced system designed for higher-acuity care.

The PressureGuard Protocol is a premium therapeutic mattress system designed for patients at high risk of pressure injuries who need more than standard dual therapy. It combines alternating pressure to continuously cycle weight redistribution, low air loss to manage heat and moisture at the skin surface, and powered flotation to deliver a more refined, clinical-grade support environment.

Built for hospital, long-term care, and higher-acuity home care settings, this system is designed for situations where patient needs can change throughout the day and caregivers need a therapy surface that adapts without requiring a system change.

Who Is This Mattress Best For?

• Patients at high risk for pressure injuries requiring advanced multi-mode therapy
• Patients with existing wounds or compromised skin needing clinical-grade support
• Individuals requiring both pressure redistribution and advanced microclimate management
• Hospital, long-term care, and higher-acuity home care environments
• Caregivers managing complex patients where therapy needs change frequently

Key Features at a Glance

• Alternating pressure therapy continuously redistributes weight to relieve pressure points
• Low air loss therapy manages heat and moisture at the skin surface
• Powered flotation mode for enhanced patient comfort and clinical support
• Advanced airflow coverlet for superior microclimate management
• Static mode for safe and easy patient transfers
• Designed for hospital, long-term care, and high-acuity home care settings

Why Choose the PressureGuard Protocol?

The PressureGuard Protocol is built for situations where a standard alternating pressure and low air loss system is not quite enough. The addition of powered flotation mode sets it apart — this feature provides a more immersive, clinical-grade support environment that reduces shear and friction forces on already-compromised skin, which standard air cycling alone does not fully address.

The advanced airflow coverlet delivers low air loss directly at the skin surface rather than simply through the mattress body — a meaningful difference for patients with significant moisture management needs or fragile skin integrity.

For patients at Stage 3–4 pressure injuries, post-surgical skin graft cases, or any situation where multiple skin risk factors are present simultaneously, the Protocol offers the clinical depth to address all of them in one system. If you are unsure whether this level of therapy is appropriate, call us at 866-218-0902 and we can help assess the right fit.

Key Specifications

• Therapy Type: Alternating Pressure + Low Air Loss
• Modes: Alternating, Powered Flotation, Static
• Cover: Advanced airflow coverlet
• Use: Hospital, long-term care, and home care
• Focus: Pressure redistribution, microclimate management, and patient comfort

Compare Similar Systems

• Protekt Aire 9000BL — high-capacity alternating pressure and low air loss system
• Invacare microAIR MA500 — proven dual therapy with heel relief and cell-on-cell base
• Protekt Aire 5000DX — strong mid-tier dual therapy system for comparison

View all Low Air Loss Mattress Systems →

Helpful Guides

Comparing therapy options or not sure which system is right for your patient? These guides can help:

• Best Mattress for Bed Sores (2026) — Complete Guide to Pressure Relief Systems — compares every level of support from foam overlays to advanced therapy systems
• The Difference Between Lateral Rotation and Alternating Pressure Low Air Loss Mattresses — explains when each advanced therapy type is the right clinical choice

Call 866-218-0902 for expert help choosing the right mattress →