SKU: 70265899771

Epiduo

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Description

EpiduoEpiduo Description A medicated gel designed to combat acne using two active ingredients. Adapalene is a topical retinoid that helps manage skin cell turnover, keeping your pores clear. Benzoyl peroxide is an antiseptic that helps lower the number of bacteria on your skin that cause acne. Essential Information What is Epiduo? Epiduo is a gel you apply to your skin, containing two active ingredients to help reduce and ease acne. It's meant for daily

Epiduo Description
A medicated gel designed to combat acne using two active ingredients.
Adapalene is a topical retinoid that helps manage skin cell turnover, keeping your pores clear.
Benzoyl peroxide is an antiseptic that helps lower the number of bacteria on your skin that cause acne.

What is Epiduo?

Epiduo is a gel you apply to your skin, containing two active ingredients to help reduce and ease acne. It's meant for daily use, so you'll need to apply a small amount to the affected areas each day.

Acne occurs when your skin's glands produce too much oil. This can make normally harmless bacteria on your skin become aggressive, leading to inflammation. Additionally, a build-up of dead skin cells can block your pores, which may also contribute to acne.

Epiduo contains two active ingredients. The first is adapalene, which helps control the growth of skin cells and reduces inflammation. The second is benzoyl peroxide, an antiseptic that decreases the bacteria on your skin. Together, these ingredients aim to clear up your acne and help keep it in check moving forward.

If you're considering using Epiduo for your acne, you'll need a prescription. This allows a clinician to ensure it's suitable for your skin and that you're receiving the most effective treatment for your acne.

How does Epiduo work?

Epiduo has two active ingredients that work together to help lessen your acne symptoms.

The first active ingredient in Epiduo is adapalene, a type of medicine known as a retinoid. Retinoids, such as adapalene, help control the growth, multiplication, and shedding of skin cells, and they also help to reduce inflammation.

Adapalene works by controlling the growth and shedding of skin cells, which helps to prevent the accumulation of dead skin cells in or around your pores. This should reduce the number of 'microcomedones' you get. Microcomedones are tiny acne blemishes that you can't see, but if not treated, they can turn into larger spots. Adapalene tackles these early stages of acne, clearing them up before they become more noticeable.

The second active ingredient in Epiduo is benzoyl peroxide, an antiseptic that helps reduce the bacteria on and in your skin. It lowers the levels of a skin bacteria called P. acnes, which is generally harmless but can cause inflammation and pus when it mixes with excess skin oil. By reducing the bacteria that can lead to inflammation and infection, it should help improve your acne.

Are there different doses of Epiduo?

Certainly. There are two Epiduo dosage options available, depending on the severity of your acne. The lower dose has 0.1% w/w adapalene and 2.5% w/w benzoyl peroxide, while the higher dose includes 0.3% w/w adapalene and 2.5% w/w benzoyl peroxide. This means the lower dose contains 1 mg of adapalene and 25 mg of benzoyl peroxide per gram of gel, and the higher dose has 3 mg of adapalene per gram of gel.

How is Epiduo different to other treatments for acne?

Epiduo is a treatment that combines two ingredients: the topical retinoid adapalene and the antiseptic benzoyl peroxide. Each of these can be used separately to treat acne, but when combined in Epiduo, they work together to help clear up current acne and prevent future breakouts.

Tretinoin is quite similar to adapalene as both are topical retinoids and work effectively. In a study involving 150 people with acne, participants were randomly assigned either adapalene gel 0.1% or tretinoin gel 0.025%. Over 70% of individuals in both groups experienced either complete clearance or significant improvement of their acne. However, those using tretinoin reported more frequent and severe skin irritation compared to those using adapalene, indicating that adapalene might be a slightly better choice for those with sensitive skin.

How well does Epiduo work for acne?

Epiduo has proven to be an effective treatment for acne in clinical trials. In a study involving 452 participants with acne, who were treated with Epiduo (containing 0.1% adapalene and 2.5% benzoyl peroxide), noticeable improvements in acne symptoms were observed as soon as the first week. No one in the trial discontinued the treatment due to ineffectiveness, and only 2% stopped because of side effects.

This indicates that Epiduo is a safe and effective choice for treating acne in the long run.

Can you use Epiduo if you’re pregnant or breastfeeding?

Epiduo isn't safe to use if you're pregnant. If you are expecting or planning to start a family soon, have a chat with your clinician about other acne treatment options.

You can use Epiduo while breastfeeding, but make sure not to apply it on your chest or breasts to prevent your baby from coming into contact with the medicine.

Important Information

Epiduo isn't right for everyone, and there are a few things you should know when using it.

Here's all the official information on it. If anything isn't clear, just let our clinician know, and they can discuss it with you.

Epiduo 0.1% / 2.5% Gel | Epiduo 0.3% / 2.5% Gel

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SKU: 70265899771

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A reader
Whiting, US
★★★★★ 5
My favorite new mineral sunscreen!
Style: SPF 50 Roll On, Size: 3 Fl Oz (Pack of 1)
This is my favorite new mineral sunscreen! I've been searching for years for a product that is easy to apply, not messy, and doesn't show up too white. This roll-on is the perfect solution. I keep it near the front door and quickly roll the sunscreen on my hands, arms, and chest before leaving the house. The sunscreen applies so quickly and uniformly-- there are no bare spots or messy globs to rub in. Also, the roll-on keeps the sunscreen from oozing out of the tube and getting all over everything. Finally, the roll-on method also eliminates the frustration of having half-filled tubes and pumps where you can't even access the sunscreen when the tube gets low. Here's hoping this doesn't happen with the roll-on. Thank you Sun Bum for creating this wonderful product. I also love the reasonable price.
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Reviewed in the United States on October 24, 2025
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Cathy mccann
Whiting, US
★★★★★ 5
great product - it must be blended in well
Style: SPF 50 Roll On, Size: 3 Fl Oz (Pack of 1)
Love this stuff. The roll-on makes it easy to apply on the go. It leaves a white streak unless you blend it in. I don't mind the white streak - at least I know I applied the product.
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Reviewed in the United States on February 4, 2026
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Justin S
Dallas, US
★★★★★ 4
Good product, a little pricey though
Style: SPF 50 Roll On, Size: 3 Fl Oz (Pack of 1)
Pretty good consistency and easy to be applied evenly. Much better than the sunscreen products I used before
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Reviewed in the United States on May 29, 2025
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Ryne n.
Battle Creek, US
★★★★★ 5
Perfect sunscreen
Style: SPF 50 Roll On, Size: 3 Fl Oz (Pack of 1)
I love the roll on sunscreen. It is quicker to apply and my little one can help without squeezing sunscreen everywhere. Will buy again.
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Reviewed in the United States on June 14, 2025
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Amazon Customer
Waukegan, US
★★★★★ 5
Roll on is so easy to use.
Style: SPF 50 Roll On, Size: 3 Fl Oz (Pack of 1)
Favorite brand and the roll on is so easy to use
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Reviewed in the United States on June 3, 2026

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