SKU: 73337315968

McKesson 5-Liter Compact Concentrator with Oxygen Sensing Device

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Description

McKesson 5-Liter Compact Concentrator with Oxygen Sensing Device< The McKesson 5 Liter Compact Concentrator with Oxygen Sensing Device (146 525DS) is a reliable, compact 5 LPM home oxygen concentrator built on the proven DeVilbiss 525DS platform 34% more compact than traditional 5 liter concentrators, making it noticeably easier to position in smaller rooms, beside a bed, or anywhere space is limited. At 36 lbs with smooth rolling casters and top and side handles, it moves easily between rooms for patients who use

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The McKesson 5-Liter Compact Concentrator with Oxygen Sensing Device (146-525DS) is a reliable, compact 5 LPM home oxygen concentrator built on the proven DeVilbiss 525DS platform — 34% more compact than traditional 5-liter concentrators, making it noticeably easier to position in smaller rooms, beside a bed, or anywhere space is limited. At 36 lbs with smooth-rolling casters and top and side handles, it moves easily between rooms for patients who use oxygen throughout the day.

The 146-525DS includes an exclusive Oxygen Sensing Device (OSD) as standard — continuously monitoring oxygen purity output to ensure reliable, accurate delivery and alerting the user if levels fall outside safe parameters. Turn-Down Technology automatically reduces system pressure at lower flow settings, cutting stress on compressor bearings and internal fittings by up to 35% and reducing power consumption — extending component life and lowering electricity costs over time. The recessed humidifier nook protects connections from accidental damage. Operates at 48 dBA for quiet home use. HCPCS code E1390.

5 LPM continuous flow · 36 lbs · 48 dBA · 87%–96% O2 · OSD oxygen sensing · Turn-Down Technology · Compact design · HCPCS E1390 · Flame-retardant cabinet. Prescription required before shipment.

Prescription Required A valid prescription from a licensed physician or respiratory therapist is required before this item can be shipped. Flow rate settings must be configured according to your physician's instructions. If you need assistance obtaining or submitting your prescription, call us at 866-218-0902 — we are happy to help coordinate with your provider. Mon–Fri 9AM–5PM · Sat 9AM–3PM.
Questions about the McKesson 5-Liter Concentrator? Call 866-218-0902 — Mon–Fri 9AM–5PM · Sat 9AM–3PM · Nationwide Shipping · Local SW Florida Support

34% More Compact. OSD Standard. Turn-Down Technology.

34% More Compact · 36 lbs · Recessed Humidifier Nook The McKesson 146-525DS is 34% more compact than traditional 5-liter oxygen concentrators — a meaningful difference in smaller bedrooms, living spaces, and care environments where floor space is at a premium. At 36 lbs with smooth-rolling casters and top and side handles, it is easy to reposition between rooms throughout the day. The recessed humidifier nook is designed to protect the humidifier connection and tubing from accidental contact or damage during daily use. The flame-retardant cabinet meets safety standards for home medical equipment.
OSD Oxygen Sensing · Continuous Purity Monitoring · 87%–96% O2 The exclusive Oxygen Sensing Device (OSD) is built into every 146-525DS unit and continuously monitors the purity of the oxygen being delivered. If output drops below safe levels, the OSD triggers a visual and audible alert — providing an important layer of safety for patients using the concentrator for extended daily therapy. The unit delivers 87% to 96% oxygen concentration across its full 0.5 to 5 LPM flow range, with a lockable flow meter to prevent accidental adjustment.
Turn-Down Technology · Lower Power · Extended Component Life Turn-Down Technology automatically reduces system pressure when operating at lower flow settings — cutting stress on compressor bearings and internal fittings by up to 35% at 2.5 LPM and below. This reduces wear on key components, extends the operational life of the concentrator, and lowers power consumption compared to units without this feature. For patients running the concentrator continuously at lower prescribed flow rates, Turn-Down Technology can meaningfully reduce electricity costs over time.

Full Specifications

Model McKesson 146-525DS
Flow Rate 0.5 to 5.0 LPM continuous flow
Oxygen Concentration 87% to 96%
Oxygen Sensing OSD — continuous purity monitoring standard
Noise Level 48 dBA
Weight 36 lbs
Dimensions 24.5"H x 13.5"W x 12"D
Compact Design 34% smaller than traditional 5-liter units
Technology Turn-Down Technology — reduces system pressure at lower flow settings
Humidifier Recessed humidifier nook
Cabinet Flame-retardant
Plug Type 2-prong
Pressure Relief Valve Yes
HCPCS Code E1390
Latex Free Yes — not made with natural rubber latex
Warranty Limited warranty
Prescription Required Yes — required before shipment
Compare All Home Oxygen Concentrators Not sure if the McKesson 5-Liter is the right model for your prescription? Compare all home oxygen concentrators we carry — 5 LPM and 10 LPM models. Browse All Home Oxygen Concentrators →

Frequently Asked Questions

The McKesson 146-525DS is built on the proven DeVilbiss 525DS platform — one of the best-selling home oxygen concentrators in the category, assembled in the USA and well established in both home and clinical settings. The McKesson version adds the OSD oxygen sensing device as standard and carries the McKesson product number for facilities and providers who order through McKesson's distribution network. Call us with any questions. 866-218-0902.
HCPCS code E1390 is the billing code used for stationary oxygen concentrators under Medicare and other insurance programs. Having this code on the product does not guarantee coverage — reimbursement depends on your specific plan, your physician's prescription, and your qualifying medical condition. Contact your insurance provider or physician to determine whether this product qualifies for coverage under your plan.
The Oxygen Sensing Device (OSD) is a built-in monitor that continuously measures the purity of the oxygen being produced by the concentrator. If the output oxygen concentration drops below a safe threshold, the OSD activates both a visual indicator light and an audible alarm to alert the user and caregiver. This provides ongoing reassurance that the unit is delivering oxygen at the prescribed concentration throughout daily use.
The McKesson 146-525DS is a stationary home concentrator that requires a standard AC wall outlet to operate. It is not designed for travel or use away from a power source. If you need oxygen therapy when away from home, a portable oxygen concentrator is the appropriate solution. Browse our portable oxygen concentrators →

Compare 5 LPM Home Oxygen Concentrators

DeVilbiss · 5 LPM · Made in USA DeVilbiss 525DS 36 lbs · 5 LPM · 48 dBA · Turn-Down Technology · OSD · Made in USA
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CAIRE · 5 LPM · 40 dBA · Bundle Caire Companion 5 ECO 36 lbs · 5 LPM · 40 dBA · autoFLOW + ultraSILENT · OCSI monitoring
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Inogen · 5 LPM · Lightest Inogen At Home ~18 lbs · 5 LPM · Lightest in category · Most energy efficient
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All Home Concentrators Full Home O2 Lineup Every home oxygen concentrator we carry — 5 LPM and 10 LPM
Browse all →

Need Oxygen Away From Home Too?

The McKesson 5-Liter is designed for stationary home use and requires a wall outlet. If you also need oxygen therapy during errands, appointments, or travel, a portable oxygen concentrator is the right complement. We carry a full range of battery-powered portable concentrators — including FAA-approved models for air travel.

Browse Portable Oxygen Concentrators →

Nationwide Shipping & Local SW Florida Support

Medical Department Store ships home oxygen concentrators nationwide to residential addresses and healthcare facilities across all 50 states. Local in-person support is available at all five of our Southwest Florida locations — Venice, Sarasota, Port Charlotte, Fort Myers, and Naples. Our respiratory specialists are available before and after purchase to answer questions, assist with prescription submission, and help you get the most from your equipment.

📞 866-218-0902 · Mon–Fri 9AM–5PM · Sat 9AM–3PM · Find your nearest location →

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Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 73337315968

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4.9 ★★★★★
Based on 22 reviews
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Product Reviews
T
Verified Purchase
TL
Dallas, US
★★★★★ 5
It's Working
Scent: Smoky coffee, Size: 4 Fl Oz (Pack of 1)
I like how it softens and protect hair. I am using sparingly on my scalp and have not used enough to see hair growth yet. I have had it for a month but do not use daily. I am growing my grey hair out and I have noticed that some of the white hairs are more salt and pepper now so it naturally darkens hair. My friend who told me about the product has been using it longer and her grey hairs are pretty much unnoticed by the natural darkening effect, blending enough to give her a light brown look. I have extremely fine thin fragile hair so I leave it on instead of rinsing or washing it out per instructions, that is another reason I do not use daily on hair and scalp. So far I have not had any negative side effects by using sparingly and leaving in until weekly wash. There is a strong smokey smell but not overwhelming for me and the scent dicipates within an hour or less.so I am not bothered by it. After using product on my hair, I rub a little on my nails & cuticles. It appears to help, as my cuticles are a lot healthier now.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2024
B
Verified Purchase
Bstew
Los Angeles, US
★★★★★ 4
Ash vs. Moisture/Success?
Scent: Smoky coffee, Size: 4 Fl Oz (Pack of 1)
The product feels great on the skin and moisturizes well. Although, don't be fooled by the smokey coffee detail. I'm an avid expresso bean grinder and drinker, this is no coffee. Smells like strong chain smokers favorite corner of the house on a stressful day. Imagine ash trays and Jojoba blended. Now that that's explained, it genuinely feels great on the skin/beard/scalp. Unfortunately, I am unsure how long my wife will tolerate this as a nighttime routine.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 9, 2025
D
Verified Purchase
denise varnell
West Palm Beach, US
★★★★★ 5
Strong coffee smell. Might not be be compatible for everyone. However, product is really good.
Scent: Smoky coffee, Size: 4 Fl Oz (Pack of 1)
Love this product. May not be compatible for someone who doesn't like smell of coffee that does not detract from the product. it's really good for hair.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 5, 2026
N
Verified Purchase
Natalie
Natrona Heights, US
★★★★★ 3
So far nothing amazing
Scent: Smoky coffee, Size: 4 Fl Oz (Pack of 1)
So I’ve been using for a couple of weeks now and I haven’t noticed any difference. I am going to continue on. I don’t know if it takes time for it to actually show some results. I will say two things about it. It comes solid for 12 my jar cracked and broken And it’s non-returnable so I just have to deal with it so that’s unfortunate after paying $20 second of all it is a solid mass so you have to put it in your hands and kind of warm it up for it to become any sort of an oil and I wouldn’t even consider it an oil at that it’s more of like a cream once you warm it up in your hands, but it doesn’t make your hair greasy. I use a small amount I would think that the jar would last a long time given that you don’t need a lot to get through to your scalp unfortunately, with my jar being cracked, I don’t know how that’s gonna affect the longevity of the product And it does have a smell think of burnt coffee beans that will dissipate after about an hour to an hour and a half after putting it on, but if you’re not putting it on, I’m just going to bed. It might be become an issue. I’m gonna wait it out. I hope I do see results from doing this but again so far nothing.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 15, 2025
M
Verified Purchase
megan moyes
San Leandro, US
★★★★★ 5
Wonderful product
Scent: Smoky coffee, Size: 4 Fl Oz (Pack of 1)
I used this on a bald spot I had and it worked extremely well. Consistency is key though it needs to be used every day
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 3, 2026

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