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Description
Renue Blue Face SerumRenue Blue Face & Hand Serum Renue Blue Face & Hand Serum works at the cellular level to deliver time released actives that restore NAD to improve skin's texture, firmness, and dermal matrix. The epitome of science and performance, Renue Blue Face & Hand Serum works renews cells from within using a proprietary Liposomal Methylene Blue with NAD Complex (NAD+, NMN, and NR)science backed nutrients that provide nourishment on the cellular level. Renue
Renue Blue Face & Hand Serum
Renue Blue Face & Hand Serum works at the cellular level to deliver time released actives that restore NAD⁺ to improve skin's texture, firmness, and dermal matrix.
The epitome of science and performance, Renue Blue Face & Hand Serum works renews cells from within using a proprietary Liposomal Methylene Blue with NAD⁺ Complex (NAD+, NMN, and NR)—science-backed nutrients that provide nourishment on the cellular level.
Renue Blue works at the cellular level to deliver time-released actives that restore NAD⁺ to improve skin's texture, firmness, and dermal matrix.
Nano-sized liposomes penetrate quickly and deeply into dermal layers to deliver a very high concentration of active ingredients that provide unique therapeutic benefits over all other serums.
Expertly formulated with liposomal NAD⁺ Complex (NAD+, NMN, and NR) and Methylene Blue, along with Apocynin, and Glutathione, this potent delivery system offers a deeper penetration of key ingredients into the skin's surface to combat the most visible signs of aging and promote vibrant, youthful-looking skin.
Use day and night with Renue Blue Face Creme. Suitable for all skin types.
METHYLENE BLUE
Methylene Blue has been studied for a wide range of ailments, many of which are aging-related illnesses, and there are currently over 20,000 studies on Pubmed. One study conducted at the University of Maryland tested the potential dermal anti-aging benefits of four antioxidants, one of which was Methylene Blue.
Among all of the antioxidants studied, Methylene Blue was by far, the most effective.
The study was conducted by the Department of Cell Biology & Molecular Genetics, at the University of Maryland.
In the study, researchers tested out four antioxidants on the skin, one of which was Methylene Blue. The second one was N. Acetyl Cysteine, or NAC, a very popular antioxidant, often taken as a supplement. The last two were MitoQ and mTEM - both of which are mitochondrial targeting antioxidants.
They applied each one topically to skin fibroblasts of healthy middle-aged adults, adults 80 and older and from people with progeria.
For most studies, skin fibroblasts are obtained through a non-invasive procedure that involves numbing at the site and taking a punch skin biopsy sample.
Progeria is an extremely rare genetic condition characterized by dramatic and rapid aging. It causes severe hardening of the arteries at a young age, and often those afflicted don't live past their teenage years.
Some researchers believe that Progeria may hold the key to understanding the precise causes of aging - so that it can be slowed down.
For this study, the Progeria fibroblasts were used as an accelerated model for normal aging - because they share many of the features in common with normal aging.
One part of the study looked at the effectiveness of these antioxidants to decrease oxidative stress. Oxidative stress plays a major role in the aging process in the skin, much of which is driven by UV exposure.
Among all of the antioxidants studied, Methylene Blue was the most effective.
It reduced mitochondrial reactive oxygen species, and promoted skin cell proliferation - which involves an increase in the cell division rate and that leads to a higher number of new, healthy cells created during cell turn-over.
The normal skin and the progeria skin treated with the Methylene Blue, showed much higher skin proliferation levels.
Research shows that as a person ages, proliferation of cells in the basal (or deepest) layer reduces. The epidermis (or the outer layer) then becomes thinner. The nutrition supply to the outer layer then weakens because of dysfunction in the deeper layers.
This process of decreased proliferation in the skin, is associated with senescence. Senescent cells, also known as zombie cells, can cause a lot of damage. They are cells that eventually stop multiplying, yet they don't die off like they should. Instead, they remain in the body and continue to release damaging chemicals that trigger inflammation.
In the second part of the study, cellular senescence was examined.
Different fibroblasts were used and treated with Methylene Blue. Two fibroblasts from people over 80 were used and two fibroblasts from people under 30 were used.
The over 80 fibroblasts showed increases in biomarkers of senescence. When treated with Methylene Blue, there was a reduction in cellular senescence, especially notable for the older skin fibroblasts. This showed that Methylene Blue is effective at reducing cellular senescence.
The study revealed that skin treated with Methylene Blue had an increase in skin thickness and improved levels of skin hydration.
This is important because skin thickness and loss of hydration are issues of aging skin. Dermal thickness decreases by about 6% every decade.
Xiong, ZM, O’Donovan, M., Sun, L., et al. Anti-Aging Potentials of Methylene Blue for Human Skin Longevity. Sci Rep 7, 2475 (2017) (https://doi.org/10.1038/s41598-017-02419-3). Licensed under CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Disclaimer – Neither the license nor link to the foregoing publication constitutes or implies any sponsorship or affiliation with, or endorsement or approval of Renue By Science by the authors.
RENUE™ - 2 Step Skin Rejuvenation Protocol
RENUE SERUM IS QUICKLY ABSORBED
Serums are made of very small molecules that penetrate your skin faster and more effectively, carrying the active ingredients to deeper layers and into systemic circulation.
Step 1: Apply face or body serum for penetration to deepest skin layers and systemic circulation.
Allow to soak in for 1-2 minutes
RENUE LOTION PROTECTS SURFACE LAYER
The thicker, more emollient ingredients in our Lotion and Face Creme concentrate more active ingredients in the surface layer.
Step 2: Apply Renue Face Creme, Lotion, or your favorite moisturizer
*note - Renue body lotion can be used alone, as the liposomes will also reach deep layers and systemic circulation, but in lesser quantities than serums. It is more effective to apply the serum first, then the lotion.
What's the ideal pH for skin-care products?
You want to look for skin-care products with a pH of 5.5. If anything, they could be as low as 4.5 and as high as 7. The general rule is slightly acidic is preferred for the best complexion.
What pH are Renue™ Products?
Renue™ NAD+ Skincare products are on the optimal 5.5 mark on the pH scale.
High pH (8 to 14)
Skin-care products with a high pH level (also known as alkaline) pose the biggest threat to your skin's pH and acid mantle. That tight, squeaky-clean feeling you might experience after washing your face is the truest sign of cleansers with a high pH and damaged skin barrier. They, as well as other alkaline skin-care products, tend to strip away sebum and natural oils.
Low pH (1 to 6)
Because products with a low pH are at a level closer to skin's natural pH, they will more effectively work with your skin and help cell turnover gently. They're more likely to keep skin bright and smooth, instead of flaky and angry.
However, certain products can be too low of a pH for skin and irritate it. At-home peels and other acid-spiked products tend to have a lower pH level, making them great exfoliants but just as stripping as products with a high pH.
These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Shipping Notes
Free Standard Shipping on $100+ Orders to the USA.
Except Preorder products are shipped in 48 hours.
Delivery to the USA:
Standard Shipping : 3-10 business days
If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
We offer a 30-day return/exchange service after receiving.
Final sale items are not eligible for returns or exchanges.
To process your return/exchange, please contact us at [email protected]
This turned out to be a really solid purchase and honestly exceeded my expectations. Sometimes products online look great in the listing but end up feeling cheap or disappointing once they arrive — thankfully that wasn’t the case here at all.
Right away, I noticed the quality felt much better than expected. Everything feels sturdy, well-finished, and designed with actual everyday use in mind. It doesn’t feel flimsy or poorly made, and that immediately gave me confidence that it’ll hold up well over time.
Another thing I appreciated was how easy everything was to set up and use. No confusion, no unnecessary complications, and no fighting with instructions. It worked correctly right away and did exactly what I needed it to do.
What really stands out after using it consistently is the reliability. It performs smoothly every time without any annoying little issues or frustrations. That may sound simple, but products that are dependable and hassle-free are honestly worth their weight in gold these days.
A few things I really liked:
Solid overall build quality
Easy and straightforward to use
Reliable performance
Feels durable and well-designed
Looks better in person than expected
Great value for the price
Overall, I’m extremely happy with the purchase. It’s one of those products that quietly makes life easier without demanding attention, and those are usually the best kinds of purchases.
Definitely an easy 5-star review from me. Would absolutely recommend it.
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Reviewed in the United States on May 28, 2026
R
Verified Purchase
richard
Dallas, US
★★★★★ 5
Precise fit, looks great, easy installation
Color: Crystal Clear
t
This a great product! I
It installed in under 5 minutes- so easy .Precision fit
for my Neo laptop. Cover is crystal clear so actual color of my laptop isn't changed. Also comes with a screen protector and keypad protector.
Well worth the price.
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Reviewed in the United States on May 26, 2026
M
Verified Purchase
Michael Y
Birmingham, US
★★★★★ 4
Durable
Color: Crystal Indigo
Great product, looks great and durable.
The price is reasonable.
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Reviewed in the United States on May 9, 2026
T
Verified Purchase
thea 𝜗𝜚 ࣪˖ ִ𐙚
Belleville, US
★★★★★ 5
awesome simple case!
Color: Crystal Clear, Color: Crystal Clear
i got the clear case for my citrus neo which is exactly what i wanted! the beautiful color still shines through and the size fits perfectly. the case was easy to put on and feels secure + the feel of it is very smooth and feels nice. there’s padding at the bottom for the lil standers which is nice! compatibility is perfect size. didn’t use the screen protector because it’s not the best but i don’t care abt using it.
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Reviewed in the United States on May 26, 2026
E
Verified Purchase
Eddy
Bozeman, US
★★★★★ 5
Perfectly fit
Color: Crystal Clear
I recently purchased a Mac Neo protective case, and it has exceeded my expectations. The case fits my laptop perfectly, with precise cutouts that ensure all ports are easily accessible and well-aligned. I especially appreciate the crystal-clear design, which maintains the original look of the device while providing solid protection. The included keyboard cover is a great bonus—it feels comfortable to type on and doesn’t interfere with responsiveness. Overall, the case combines functionality, protection, and aesthetics very well.
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