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Description
Mouse IgA OneStep ELISA KitProduct Specification Antigen IgA Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Ms Purification Protein A Stability & Storage 2 to 8 C as supplied. Kit Precision Intra assay: 2. 8% Inter assay: 3. 8% Sample type Cell culture supernatant, Serum, Plasm Assay type Sandwich (quantitative) Sensitivity 0. 046 ng ml Range 0. 16 ng mL 10 ng mL Recovery Cell culture supernatant: 94% Serum: 93% Plasm: 90% Assay time 60 minutes Species
Product Specification
| Antigen | IgA |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Ms |
| Purification | Protein A |
| Stability & Storage | 2 to 8 °C as supplied. |
Kit
| Precision | Intra-assay: 2.8%； Inter-assay: 3.8% |
| Sample type | Cell culture supernatant, Serum, Plasm |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.046 ng/ml |
| Range | 0.16 ng/mL – 10 ng/mL |
| Recovery | Cell culture supernatant: 94% Serum: 93% Plasm: 90% |
| Assay time | 60 minutes |
| Species reactivity | Mouse |
Background
Mouse IgA (Immunoglobulin A) is a key antibody isotype that plays a critical role in mucosal immunity. It is predominantly found in mucosal surfaces such as the intestines, respiratory tract, and urogenital tract, where it serves as the first line of defense against pathogens. Mouse IgA exists in two forms: monomeric IgA in the serum and dimeric or polymeric IgA in mucosal secretions. The latter is often associated with a secretory component (SC) and a joining (J) chain, which facilitate its transport across epithelial cells and enhance its stability in mucosal environments. Mouse IgA functions by neutralizing pathogens, preventing their adhesion to epithelial cells, and promoting their clearance through mechanisms such as immune exclusion. It also plays a role in maintaining homeostasis with commensal microbiota. Due to its importance in mucosal immunity, mouse IgA is widely studied in research related to infections, allergies, and inflammatory diseases.
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