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Description
p27 Recombinant Rabbit mAb (SDT-R350)Product Specification Host Rabbit Synonyms Cyclin dependent kinase inhibitor 1B, Cyclin dependent kinase inhibitor p27, p27Kip1, Cdkn1b, KIP 1 Location Cytoplasm, Nucleus Accession P46414 Clone Number SDT R350 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0.
Product Specification
| Host | Rabbit |
| Synonyms | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b, KIP-1 |
| Location | Cytoplasm, Nucleus |
| Accession | P46414 |
| Clone Number | SDT-R350 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500-1:2000 | |
| ICC | 1:100 | |
| ICFCM | 1:50 |
Background
p27 Kip1 is a member of Cip/Kip family of proteins, leading to cell cycle arrest in G1 phase. Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung. In pathology, it can be used for the identification of thyroid adenoma and thyroid follicular carcinoma.
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