SKU: 11556671858

Alexa Fluor® 488 Mouse Anti-Human CD11a/CD18 Antibody (S-2969)

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Description

Alexa Fluor® 488 Mouse Anti-Human CD11a/CD18 Antibody (S-2969)Product Specification Host Mouse Antigen CD11a CD18 Synonyms Integrin alpha L; CD11 antigen like family member A; Leukocyte adhesion glycoprotein LFA 1 alpha chain (LFA 1A); Leukocyte function associated molecule 1 alpha chain; ITGAL; CD11A; Integrin beta 2; Cell surface adhesion glycoproteins LFA 1 CR3 p150,95 subunit beta; Complement receptor C3 subunit beta; ITGB2; MFI7 Location Cell membrane Accession P05107P20701 Clone Number S 2969 Antibody Type

Product Specification


Host Mouse
Antigen CD11a/CD18
Synonyms Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A); Leukocyte function-associated molecule 1 alpha chain; ITGAL; CD11A; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; ITGB2; MFI7
Location Cell membrane
Accession P05107、P20701
Clone Number S-2969
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood leukocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD18, also known as integrin β2, is a 95 kDa glycoprotein that is a crucial component of several β2 integrins. These integrins are heterodimeric type I transmembrane proteins composed of a variable alpha chain (CD11a-d) and the common beta chain CD18. The CD18 protein is encoded by the ITGB2 gene in humans. It plays a significant role in cellular adhesion and immune responses. When CD18 binds with different alpha chains, it forms various heterodimers such as lymphocyte function-associated antigen-1 (LFA-1) with CD11a, and Macrophage-1 antigen receptor (Mac-1) with CD11b. These heterodimers are involved in processes like leukocyte adhesion to endothelial cells, phagocytosis, and immune cell activation. Deficiencies in CD18 expression can lead to adhesion defects in white blood cells, impairing the immune system's ability to fight infections.

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SKU: 11556671858

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Kayann
Lowell, US
★★★★★ 5
Quality and long lasting
Size: Extra Small (Pack of 2), Color: Blue
Highly Recommended!!! My 9 Shihtzu’s absolutely love the smell the durability and taste their thick so last long Thankfully I have to buy these every month!!!
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Reviewed in the United States on January 25, 2026
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Kindle Customer
Omaha, US
★★★★★ 4
Is this safe for my dog if she chews off little pieces.
Size: Small/Medium, Color: yellow
My Chihuahua loves this, however I want to know is it safe for my dog to swallow? She chews on it and gets little pieces of it and swallows them.
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Reviewed in the United States on June 4, 2026
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Valarie Amundsen
West Palm Beach, US
★★★★★ 5
Chews
Size: Extra Small, Color: Blue
Chewy toys to keep my dogs, teeth, healthy very important. This was a very good price and I highly recommend buying it for your puppy.
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Reviewed in the United States on June 11, 2026
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Judy
Natrona Heights, US
★★★★★ 3
Dog likes some
Size: Extra Small, Color: Blue
Puppy will chew on this but not favorite. Over time it gets sharp pieces and dog could ingest. Not sure how safe for a small dog. Affordable but not long lasting.
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Reviewed in the United States on March 30, 2026
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Teresa mosier
San Leandro, US
★★★★★ 5
Pug approved
Size: Extra Small, Color: Blue
Bought for my pug to teeth on when he was a puppy. He's almost year old and he still packs his little bone around
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Reviewed in the United States on June 10, 2026

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