SKU: 13200119608

Alexa Fluor 488-Labeled CD19 His Tag Protein, Human

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Description

Alexa Fluor 488-Labeled CD19 His Tag Protein, HumanProduct Specification Species Human Synonyms CD19,B4,CVID3,MGC12802 Accession P15391 1 Amino Acid Sequence Pro 20 Lys 291 with His Tag at C Terminus Expression System CHO Molecular Weight 40 45kDa (Reducing) Conjugation Alexa Fluor 488 Tag His Tag Physical Appearance Liquid Storage Buffer PBS, pH7. 4 Stability & Storage 12 months from date of receipt, lyophilized powder stored at 20 to 80. 3 months, 20 to 80 under sterile conditions after

Product Specification


Species Human
Synonyms CD19,B4,CVID3,MGC12802
Accession P15391-1
Amino Acid Sequence

Pro 20-Lys 291 with His Tag at C-Terminus
Expression System CHO
Molecular Weight

40-45kDa (Reducing)
Conjugation Alexa Fluor® 488
Tag His Tag
Physical Appearance Liquid
Storage Buffer

PBS, pH7.4
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Wang SY, An WH, Wang ZS, Wang WL, Zhang B, Xu KL, Guo SL, Gao M, Li B, Huang L, Tian HH, Guo WY, Wang HR. Incidentally cured psoriasis in a patient with refractory/relapsed diffuse large B-cell lymphoma receiving CD19 CAR-T cell therapy: a case report. Front Immunol. 2024 Oct 24; 15: 1418768.

Background

CD19, also known as B-lymphocyte antigen or Cluster of Differentiation 19, is a single-pass type I membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains. It is expressed on follicular dendritic cells and B cells, being present from the earliest recognizable B-lineage cells during development to B-cell blasts, but is lost upon maturation to plasma cells. CD19 primarily functions as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, leading to binding by Src-family kinases and recruitment of PI-3 kinase. Mutations in the CD19 gene are associated with severe immunodeficiency syndromes, characterized by diminished antibody production. CD19 has been shown to interact with CD81, CD82, Complement receptor 2, and VAV2.

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Exchange/Return Notes
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SKU: 13200119608

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4.5 ★★★★★
Based on 13 reviews
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Product Reviews
S
Verified Purchase
Simon
Whiting, US
★★★★★ 4
Good Multipurpose Hub, Some Limits on Power Draw
I use this with a Dell Latitude 7430 with a 65W charger, and it works fine as a docking hub. The only problem I've encountered is when rebooting, the boot will pause with a warning message to tell me that the laptop may encounter reduced performance because it isn't able to receive the full 65 watts. I don't get that warning if I'm not running the power supply through the hub. Otherwise, if I just use the hub as a port extender everything is fine. It has a compact design and is reasonably lightweight. It would be ideal for travel. Like my other Anker hubs, it's well constructed and doesn't feel cheap although it's good value for money.
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Reviewed in the United States on June 9, 2026
T
Verified Purchase
The Gabers
Lake Worth, US
★★★★★ 5
I don't know how I ever lived without it.
I'm very happy with this device. My laptop doesn't have an ethernet port and only has one USB-C SuperSpeed port, so I bought an ethernet to USB-C cable to connect my ethernet switch to the Anker and into my laptop's USB-C port, and it works great. I don't need a fast internet connection for the things I do, so my service is only a 50mbps symmetrical up/down connection, and that's what I get even while transferring files from my external between other devices, charging my phone, and using composite devices. I bought the Anker 100W Compact and Foldable USB C Charger for it and it charges my S24 extremely fast. It's very well built, yet super lightweight. I love the sleek, slender design. It's the perfect size to easily slide into a pocket, store in a desk drawer, or keep handy in a laptop case or backpack. Using it is easy. Just plug it into your computer and plug your devices into it. Just make sure you have a power supply for it if you're charging or powering other devices, using external storage, or running anything else that taxes USB power. I have had ZERO connectivity issues with it — no random disconnect/reconnect blips, no failed transfers for huge amounts of data that have taken up to 45 minutes, no static his or crackle when my headset is running through it... no problems at all. It's actually kind of spooky now that I think about it... I can't recall a time I've ever had a similar device that didn't have some nuance that got under my skin, like a loose connection, random disconnections, having to reinstall the drivers all the time, or having to troubleshoot just to get it connected for the first time. The most stress I've put it through was with my keyboard connected, ethernet running through it, my S24 charging and transferring about ~20gb of pictures and videos to my 2T external HD at the same time that my laptop was transferring about ~500gb of media and documents to the HD, too, and I was surprised by how warm it DIDN'T get. My only complaint is trivial and unique to my situation — I wish output cord was longer. About six inches would do. My laptop sits up on an adjustable stand that clamps to my desk, and the end where the output cord is hangs a few inches off of my desk. This puts extra stress on the USB-C port and can wear it out faster or damage it. I haven't had a use for the HDMI port yet, but I eventually will. I use all of the other ports for my work and personal devices, though. These include: a 2tb external hard drive; a Poly Blackwire 3320 Series headset; a dongle for a wireless mouse/keyboard combo or a wired keyboard and a dongle for a wireless mouse; my Galaxy S24 charges and transfers files through it super fast; I have several thumb drives ranging from 20gb to 512gb that I regularly use; I recently bought an RCA/S Video-to-USB converter to digitize old home movies I plug into it, too.
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Reviewed in the United States on October 25, 2025
C
Verified Purchase
Carl H
Cuba, US
★★★★★ 5
Anker wins again.
Worked well for usb hub but hdmi was not reliable. Disappointed because usually Anker products are good quality. UPDATE: Anker voluntarily offered a refund so my faith in Anker has been fully restored.
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Reviewed in the United States on May 5, 2026
J
Verified Purchase
Jay Hammer
Chelsea, US
★★★★★ 5
Perfect with a MacBook
The Anker USB C Hub works great with my MacBook Air. I paired it with the Anker 100W MacBook charger which plugs directly into the USB C Hub so I only have to plug in one cable like a true docking station. My Apple MagSafe charger stays in my briefcase so I always have a charger when I'm away from my desk. I also plug in my external monitor and an external hard drive. I highly recommend this product!
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Reviewed in the United States on June 5, 2026
E
Verified Purchase
E. E. Weinreb
Phoenix, US
★★★★★ 5
ASURION 4-Year Housewares Plan - An Excellent ROI
The ASURION 4 Year housewares protection plan was definitely one of the best investments that I've made to date. I had a large, 12,000 BTU portable air conditioner that stopped working properly in its third year of use--one year after the manufacturer's warranty had expired--essentially leaving me with a glorified hot air fan. I proceeded to file a claim on my ASURION 4 Year housewares protection plan. The process could not have been easier and did not require much documentation since the plan was already linked to my prior purchase of the AC off Amazon. I received an Amazon gift card within minutes of filing the claim, thereby definitively demonstrating ASURION's broad coverage scope, reliability, and overall value. As such, I used part of the gift card to purchase another four-year plan on a replacement AC unit that's now sitting in my office. Hopefully, I will not need to use it, but it's good to know that I have coverage if needed.
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Reviewed in the United States on April 23, 2026

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