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Description
Claudin 1 Recombinant Rabbit mAb, PBS Only (SDT-1289-55)Product Specification Host Rabbit Antigen Claudin 1 Synonyms Senescence associated epithelial membrane protein; CLDN1; CLD1, SEMP1 Immunogen Synthetic Peptide Location Cell membrane Accession O95832 Clone Number SDT 1289 55 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu Positive Sample MCF7, A431, HepG2, mouse skin, rat kidney Predicted Reactivity Bv Purification Protein A Concentration 1 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | Claudin 1 |
| Synonyms | Senescence-associated epithelial membrane protein; CLDN1; CLD1, SEMP1 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | O95832 |
| Clone Number | SDT-1289-55 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu |
| Positive Sample | MCF7, A431, HepG2, mouse skin, rat kidney |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
| IHC-P | 1:250 | Hu |
| IF | 1:200 | Hu |
Background
Claudin 1 is a 23 kDa multi-pass membrane protein in the Claudin family of epithelial tight junction proteins. Claudin-1 is expressed by epithelial cells in a wide variety of tissues as well as in Langerhans cells and dendritic cells. It is up or downregulated in many cancers and is required for the entry of hepatitis C virus into hepatocytes. It mainly expresses the peripheral neuroma (partial type of negative), derivative skin fibrous sarcoma, fibroma and deity fibroma.
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