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Description
Mouse Anti-Human CD122 Antibody (S-2880)Product Specification Host Mouse Antigen CD122 Synonyms Interleukin 2 receptor subunit beta; IL 2 receptor subunit beta; IL 2R subunit beta; IL 2RB; High affinity IL 2 receptor subunit beta; Interleukin 15 receptor subunit betaImported; p70 75 (p75); IL15RB; IL2RB Location Cell membrane Accession P14784 Clone Number S 2880 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood cells Purification
Product Specification
| Host | Mouse |
| Antigen | CD122 |
| Synonyms | Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit betaImported; p70-75 (p75); IL15RB; IL2RB |
| Location | Cell membrane |
| Accession | P14784 |
| Clone Number | S-2880 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood cells |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:2000 | Hu |
Background
CD122, also known as the interleukin-2 receptor beta (IL-2Rβ), is a key component of the IL-2 receptor complex and plays a crucial role in regulating immune responses. It is expressed on the surface of various immune cells, including T cells and natural killer (NK) cells. CD122 is involved in mediating the effects of IL-2, which is essential for the proliferation and differentiation of T cells, as well as the maintenance of regulatory T cells (Tregs). Recent studies have shown that targeting CD122 with selective IL-2 complexes can reduce immunosuppression by Tregs and enhance antitumor immunity, making it a promising target for cancer immunotherapy.
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