SKU: 17313911851

Rat Anti-Mouse CD21/CD35 antibody (S-R717)

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Description

Rat Anti-Mouse CD21/CD35 antibody (S-R717)Product Specification Host Rat Antigen CD21 CD35 Synonyms Complement receptor type 2; Complement C3d receptor; Cr2; Cr1 Location Cell membrane Accession P19070 Clone Number S R717 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of

Product Specification


Host Rat
Antigen CD21/CD35
Synonyms Complement receptor type 2; Complement C3d receptor; Cr2; Cr1
Location Cell membrane
Accession P19070
Clone Number S-R717
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:2000 Ms

Background

CD21 (CR2) and CD35 (CR1) are key complement receptors predominantly expressed on B cells and follicular dendritic cells (FDCs). CD21, also known as the C3d receptor, binds to complement fragments like C3d and iC3b, playing a crucial role in B cell activation and regulation of immune responses. It also serves as the receptor for Epstein-Barr virus (EBV) on B cells. CD35, on the other hand, binds to C3b and C4b, facilitating phagocytosis and immune complex clearance. It helps in the activation of B cells and regulation of complement activity. Both receptors are involved in antigen presentation and immune complex internalization, contributing to both innate and adaptive immune responses.

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SKU: 17313911851

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4.8 ★★★★★
Based on 27 reviews
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Product Reviews
M
Verified Purchase
Mateo Tabares Garcia
Lake Worth, US
★★★★★ 5
Excellent Product
Color: Right - Black, Size: Large
Really comfortable. Very usefull for my wrist, great shape, really smooth on the movement. Recommended to take care of you wrist.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
M
Verified Purchase
Melissa J.
Birmingham, US
★★★★★ 5
Elevates your wrist
Color: Right - Black, Size: Large, Color: Right - Black, Size: Large
This is a great tool. No wrist pain day 1. It elevates your wrist to level with the mouse so there’s no backward strain. Takes a little getting use to but well worth no pain.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 5, 2026
S
Verified Purchase
S.S.
Phoenix, US
★★★★★ 3
It's hard af.
Color: Right - Grey, Size: Small, Color: Right - Grey, Size: Small
Edit: just realized Amazon sent me a left handed one! I got this one and the g2 or whatever with the strap. The g2 is great. This one is hard though. The edges of the rest thingy. And the edges in the middle where it splits are annoying. Idk if it's a difference in the rubber pads or what. Even if this works for wrist pain, it's not worth it for the palm discomfort.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 14, 2026
S
Verified Purchase
S Wang
Fort Morgan, US
★★★★★ 5
Ergonomic and effective, but requires adjustment.
Color: Right - White, Size: Large
Bought this for improving wrist posture during long hours at the desk. What I like • The ergonomic design helps reduce wrist strain, especially during extended typing sessions. • The right-handed orientation is comfortable and natural to use. • High-quality build, feels sturdy and durable. What could be better • It takes some time to adjust to the unique design, especially if you’re used to traditional mice. • The size may not be suitable for people with smaller hands. • It could be a bit pricey compared to other ergonomic mice on the market. Bottom line: A great investment for improving wrist posture and reducing strain, but it might not be for everyone due to the learning curve and price. Perfect for users looking to enhance ergonomics, but consider alternatives if you have smaller hands or need a more budget-friendly option.
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Reviewed in the United States on April 20, 2025
M
Verified Purchase
M
Lowell, US
★★★★★ 1
It’s painful. Not worth it.
Color: Right - Grey, Size: Small, Color: Right - Grey, Size: Small
I hate it. Period. Very strong feelings about it right out of the box. Gave it a few days, and not only do I still hate it but it’s very painful to use. The rubber material is hard and has pressure points that make you come away feeling like you’ve rested your wrist on the edge of a table for too long. I come away more sore using this than not. They only have small and large sizes, I think the small is too small for me? (I’m not sure. I can tell it doesn’t fit well, but I can’t tell if it’s because it’s too small or the shape isn’t right for my wrist). In any event, I am sure the large would be too large and even if they had a medium size I still wouldn’t repurchase this. Maybe if you’ve got some meat on your bones it would be more comfortable but as you can see, I am a very thin person and this is pressing on all the wrong places. I also feel like the center valley part contributes to carpal tunnel pain because the very firm edges of each side rested right in that area, not offering any support to the valley of the wrist, and therefore creating pressure to that nerve center and the ligaments. I don’t know why they chose this material, it’s too firm. Also, I think a better design would be a little tab from the center of it sticking out and then attaching to the bottom of the mouse so that both mouse and the wrist “support” worked as one unit when moving the mouse around. I often found that I didn’t drag the wrist piece with my mouse well and that it caused even more issues. If it were comfortable I would have made a little tab myself and connected the mouse and the wrist rest together, but as it’s extremely not even remotely comfortable I’m not bothering and I’ve already started the return process.
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Reviewed in the United States on November 13, 2024

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