SKU: 17741512566

Mouse Anti-Human CD42b Antibody (S-935-7)

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Description

Mouse Anti-Human CD42b Antibody (S-935-7)Product Specification Host Mouse Antigen CD42b Synonyms GPIb, Platelet glycoprotein Ib alpha chain, GPIb alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b alpha Immunogen Recombinant Protein Location Membrane Accession P07359 Clone Number S 935 7 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%

Product Specification


Host Mouse
Antigen CD42b
Synonyms GPIb, Platelet glycoprotein Ib alpha chain, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha
Immunogen Recombinant Protein
Location Membrane
Accession P07359
Clone Number S-935-7
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution


application dilution species
FCM 1:2000

Background

Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene. Glycoprotein Ib (GPIb) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The GpIb functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V to form the glycoprotein Ib-IX-V complex. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis.

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SKU: 17741512566

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