Pay in installments of $27.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 10 - Aug 15
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Mouse Anti-Human CD155/PVR Antibody (S-2901)Product Specification Host Mouse Antigen CD155 PVR Synonyms Poliovirus receptor; Nectin like protein 5 (NECL 5); PVS Location Cell membrane Accession P15151 Clone Number S 2901 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood cells Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &
Product Specification
| Host | Mouse |
| Antigen | CD155/PVR |
| Synonyms | Poliovirus receptor; Nectin-like protein 5 (NECL-5); PVS |
| Location | Cell membrane |
| Accession | P15151 |
| Clone Number | S-2901 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood cells |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD155, also designated PVR (poliovirus receptor) and Necl-5, is a ~70 kDa primate-restricted type I transmembrane glycoprotein of the immunoglobulin superfamily that contains one V-type and two C2-type extracellular Ig-like domains, a 24-aa transmembrane segment and a 50-aa cytoplasmic tail; it serves as the cellular entry receptor for poliovirus, mediates cell adhesion by binding vitronectin and nectin-3, and engages immune receptors DNAM-1/CD226, CD96 and TIGIT to regulate NK-cell cytotoxicity, T-cell activation and tumor-cell recognition, while its expression—up-regulated by IFN-γ on endothelial cells and abundant on immature thymocytes, dendritic cells and epithelial/neuronal tumor cells—promotes cell migration, loss of contact inhibition and transendothelial migration.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy