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Description
Armenian hamster Anti-Mouse TCR β Antibody (S-3829)Product Specification Host Armenian hamster Antigen TCR Synonyms T cell receptor beta 1 chain C region Location Membrane Accession P01852 Clone Number S 3829 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Armenian hamster |
| Antigen | TCR β |
| Synonyms | T-cell receptor beta-1 chain C region |
| Location | Membrane |
| Accession | P01852 |
| Clone Number | S-3829 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Ms |
Background
The TCR β protein is a key component of the T-cell receptor (TCR), belonging to the immunoglobulin superfamily, and is primarily expressed on the surface of T cells. It is encoded by gene segments—variable (V), diverse (D), joining (J), and constant (C)—through V(D)J recombination, forming a highly diverse antigen-binding domain that recognizes antigen peptides presented by major histocompatibility complex (MHC) molecules. The TCR β chain noncovalently associates with the α chain to form a heterodimer, which constitutes the core structure of the TCR and plays a critical role in T-cell development, activation, and adaptive immune responses. Its intracellular segment is relatively short and must associate with the CD3 signaling complex to transmit antigen recognition signals into the cell, thereby initiating T-cell immune effector functions.
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