SKU: 21163711826

FITC Syrian Hamster Anti-Mouse CD28 Antibody (S-R515)

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Description

FITC Syrian Hamster Anti-Mouse CD28 Antibody (S-R515)Product Specification Host Syrian Hamster Antigen CD28 Synonyms T cell specific surface glycoprotein CD28 Location Cell membrane Accession P31041 Clone Number S R515 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Purification Protein G Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied

Product Specification


Host Syrian Hamster
Antigen CD28
Synonyms T-cell-specific surface glycoprotein CD28
Location Cell membrane
Accession P31041
Clone Number S-R515
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Purification Protein G
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5 μl per million cells in 100μl volume

Background

CD28, a 44-kDa disulfide-linked glycoprotein, is constitutively expressed on the surface of most CD4+ and CD8+ T cells. It plays a crucial role in T cell activation and signaling by interacting with its ligands CD80 (B7.1) and CD86 (B7.2) on antigen-presenting cells. CD28 enhances T cell receptor signaling, promotes cell cycle entry, and supports the survival of T cells by upregulating anti-apoptotic proteins like Bcl-2. It also preferentially promotes TH2 differentiation, aiding B cell germinal center formation and isotype switching. CD28 signaling involves multiple pathways, including PI3K, Grb2, and NFκB activation, which collectively regulate T cell proliferation, differentiation, and effector functions.

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SKU: 21163711826

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4.6 ★★★★★
Based on 14 reviews
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A
Verified Purchase
Antoinette Waikiki
Fort Morgan, US
★★★★★ 5
Good purchase and superb seller.
Format: Paperback
This is a very good book. I was very satisfied with the service I received, I got the book before the expected time. I was really supprised with the shape of the book...it was a used book but looked like brand new. I say this was superb purchase and the seller was top notch.
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Reviewed in the United States on November 4, 2013
A
Verified Purchase
Alex Hadesty
Battle Creek, US
★★★★★ 5
Great for Presentation Education
Format: Paperback
It has been some time since I have utilized Beyond Bullet Points, but this is one text book that kept with me. The point of the book is to help a presenter get their point across to the audience through Powerpoint presentations, and the book does this well. I am sure there are editions other than this one at this point, and I would definitely recommend looking into them in order to keep up to date. Starting with this book is a great idea due to its simplicity.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 24, 2014
S
Verified Purchase
S. Langley
Boise, US
★★★★★ 4
A
This is a great resource. I thought I created great presentations before. Reading this made me realize the mistakes I was making and have me a process for really improving my decks
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 29, 2014
J
Verified Purchase
John
Carnegie, US
★★★★★ 5
This book will make a difference in your presentation.
Format: Paperback
If you rely on Powerpoint-like presentation in your work, get Cliff Atkinson's Beyond Bullet Points. I had determined that improving my company's presentations had potentially very high returns so I started poking around the net and Amazon for resources to help. At first, I struck out with books that were supposed to improve presentations, but ended up being guides on technically how to use Powerpoint. That was NOT what I was looking for. Beyond Bullet Points is very different. It is a philosophy about creating presentations whose purpose is to communicate a story, not dump information. Frankly, it was not intuitive for me so I had to decide to just trust that it would work. When I was about ¾ finished, I started to really "feel" what I was doing. And, to my surprise, the most unlikely people really liked the result. In a world where most business and how-to books are nothing more that restating what you already know (or, what you know isn't true), this one is an exception. I highly recommend it!
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Reviewed in the United States on October 19, 2005
C
Verified Purchase
C. Tucker
Boise, US
★★★★★ 5
Presentations with the audience in mind
Format: Paperback
I bought this hoping it would be a guide to creating Big-3 Consulting-style slides with fancy diagrams and eye-catching graphic design. That is not what this book is. Instead, this book is about how to tell a story with slides, using the framework of a five act drama. With this method forcing you to focus on who your audience is, what they need to know, and how much time you have to tell them (as opposed to trying to shoehorn everything you know about a subject into your pitch) you end up with a presentation that finishes on time for intelligent questions from an engaged audience. Since buying the book I have given several well-received presentations using precisely that technique. With no words on screen there is no temptation to just read the bullet points, and the audience cannot think ahead of you and must instead listen to what you're saying. You have to know your material to use this method, but when you succeed your audience will be impressed with your knowledge of the subject matter. (If you're working in a group project and want to Blue Falcon a non-contributing teammate, try giving them a few of these slides to speak to.) The recommended slide format is one picture and one headline per slide, with no bullet points at all. The book suggests creating Notes Pages with an outline of your talk as a handout, since the slides themselves don't stand alone. (And that's a good thing--visual aids are supposed to *augment* the presentation, not *be* the presentation.) In conclusion, this book might not be for everyone, but it was exactly what I needed.
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Reviewed in the United States on June 15, 2018

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