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Description
LYPD3/C4.4A Recombinant Rabbit mAb (S-R222)Product Specification Host Rabbit Antigen LYPD3 C4. 4A Synonyms Ly6 PLAUR domain containing protein 3, GPI anchored metastasis associated protein C4. 4A homolog, Matrigel induced gene C4 protein (MIG C4) Location Cell membrane Accession O95274 Clone Number S R222 Antibody Type Recombinant mAb Application WB, IHC P, FCM, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer
Product Specification
| Host | Rabbit |
| Antigen | LYPD3/C4.4A |
| Synonyms | Ly6/PLAUR domain-containing protein 3, GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein (MIG-C4) |
| Location | Cell membrane |
| Accession | O95274 |
| Clone Number | S-R222 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, FCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IP | 1:50 | null |
| IHC | 1:2000 | null |
| FCM | 1:500 | null |
Background
C4.4A (Ly6/PLAUR domain-containing protein 3, LYPD3), first reported in 1998, is a tumorigenic and high-glycosylated cell surface protein that has been proven to be linked with the carcinogenic effects in different solid tumors. The elevated expression of LYPD3 is not only demonstrated to be associated with lung adenocarcinoma carcinogenesis and poor prognosis but also there is evidence that LYPD3 can lead to the initiation and development of cancers and the chemoresistance of metastatic cancers by impacting the proliferation and apoptosis of the tumor, which are involved in many important regulatory mechanisms of cancers.
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