Pay in installments of $45.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 14 - Aug 19
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Mouse Anti-human CD38 Antibody (S-R507-2)Product Specification Host Mouse Antigen CD38 Synonyms ADP ribosyl cyclase cyclic ADP ribose hydrolase 1; 2' phospho ADP ribosyl cyclase; 2' phospho ADP ribosyl cyclase 2' phospho cyclic ADP ribose transferase; 2' phospho cyclic ADP ribose transferase; ADP ribosyl cyclase 1 (ADPRC 1); Cyclic ADP ribose hydrolase 1 (cADPR hydrolase 1); T10 Location Membrane Accession P28907 Clone Number S R507 2 Antibody Type Mouse mAb Isotype IgG1 Application FCM
Product Specification
| Host | Mouse |
| Antigen | CD38 |
| Synonyms | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1); Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1); T10 |
| Location | Membrane |
| Accession | P28907 |
| Clone Number | S-R507-2 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD38, also known as cyclic ADP ribose hydrolase, is a multifunctional transmembrane glycoprotein expressed on various immune cells such as T lymphocytes, B cells, and plasma cells. It functions as both a receptor and an enzyme, playing a crucial role in cell adhesion, signal transduction, and the regulation of intracellular calcium levels. CD38 catalyzes the metabolism of nicotinamide adenine dinucleotide (NAD+), generating molecules like cyclic ADP-ribose (cADPR) and ADP-ribose (ADPR), which are involved in calcium signaling and immune responses. It is highly expressed on myeloma cells and is used as a therapeutic target for multiple myeloma and other hematological malignancies. Additionally, CD38 is implicated in various physiological processes, including inflammation, phagocytosis, and antigen presentation, making it a subject of interest in both immunology and oncology.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy