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Description
GPA33 Recombinant Rabbit mAb (SDT-248-76)Product Specification Host Rabbit Antigen GPA33 Synonyms Cell surface A33 antigen, Glycoprotein A33 Immunogen Synthetic Peptide Location Membrane Accession Q99795 Clone Number SDT 248 76 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | GPA33 |
| Synonyms | Cell surface A33 antigen, Glycoprotein A33 |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | Q99795 |
| Clone Number | SDT-248-76 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | |
| IHC-P | 1:2000 |
Background
The A33 cell-surface differentiation antigen is a glycoprotein that belongs to the immunoglobulin superfamily [PMID: 9012807]. This antigen is expressed in >95% of primary and metastatic colon cancer cells, but is absent in most normal and tumor cell types [PMID: 9245713, PMID: 16000578]. Although the exact function of this glycoprotein is unknown, antibodies developed against the A33 antigen bind to tumor cells and exhibit prolonged retention in the tumor tissue [PMID: 8656247].
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