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Description
Nectin-1/PVRL1 Recombinant Rabbit mAb (S-279-140)Product Specification Host Rabbit Antigen Nectin 1 PVRL1 Synonyms Herpes virus entry mediator C (Herpesvirus entry mediator C; HveC), Herpesvirus Ig like receptor (HIgR), Nectin cell adhesion molecule 1, Poliovirus receptor related protein 1, CD111, PRR1 Immunogen Recombinant Protein Location Secreted, Cell membrane Accession Q15223 Clone Number S 279 140 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | Nectin-1/PVRL1 |
| Synonyms | Herpes virus entry mediator C (Herpesvirus entry mediator C; HveC), Herpesvirus Ig-like receptor (HIgR), Nectin cell adhesion molecule 1, Poliovirus receptor-related protein 1, CD111, PRR1 |
| Immunogen | Recombinant Protein |
| Location | Secreted, Cell membrane |
| Accession | Q15223 |
| Clone Number | S-279-140 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:200 | null |
Background
Poliovirus receptor-related 1 (PVRL1), also known as nectin-1 and CD111 (formerly herpesvirus entry mediator C, HVEC) is a human protein of the immunoglobulin superfamily (IgSF), also considered a member of the nectins. PVRL1 is an adhesion molecule found in a wide range of tissues where it localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons. The protein has been revealed as one of the key players in mediating cellular entry of the Herpes simplex virus by interacting with the viral glycoprotein D (gD).
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