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Ships within 48 hours · Estimated delivery Jul 8 - Jul 13
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Description
Human IL-13 PBS only Pairs KitProduct Specification Antigen IL 13 Kit Range 3. 9 pg ml 250 pg ml Background IL 13 is a 132 amino acid nonglycosylated cytokine that shares common features with IL 4. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils. IL 13 signals through a receptor complex containing IL 13 R alpha 1 and IL 4 R alpha. This complex also functions as the type 2 IL 4 receptor. IL 13 bound IL 13 R alpha 2 with high affinity and can
Product Specification
| Antigen | IL-13 |
Kit
| Range | 3.9 pg/ml - 250 pg/ml |
Background
IL-13 is a 132-amino-acid nonglycosylated cytokine that shares common features with IL-4. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 bound IL-13 R alpha 2 with high affinity and can directly promote tumor cell invasiveness and the development of tissue fibrosis. Nevertheless, like IL-4, IL-13 inhibits macrophage production of TNF, IL-1β, and pro-inflammatory chemokines, but can upregulate the synthesis of IL-12 by DCs and macrophages.
Shipping Notes
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