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Description
ALOX15 Recombinant Rabbit mAb (S-R308)Product Specification Host Rabbit Synonyms Polyunsaturated fatty acid lipoxygenase ALOX15, 12 15 lipoxygenase, Leukocyte type arachidonate 12 lipoxygenase (12 LOX), Arachidonate 15 lipoxygenase (15 LOX; 15 LOX 1), Arachidonate omega 6 lipoxygenase, Hepoxilin A3 synthase Alox15, Linoleate 13S lipoxygenase, LOG15 Location Cytoplasm, Cell membrane Accession P16050 Clone Number S R308 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, ICFCM
Product Specification
| Host | Rabbit |
| Synonyms | Polyunsaturated fatty acid lipoxygenase ALOX15, 12/15-lipoxygenase, Leukocyte-type arachidonate 12-lipoxygenase (12-LOX), Arachidonate 15-lipoxygenase (15-LOX; 15-LOX-1), Arachidonate omega-6 lipoxygenase, Hepoxilin A3 synthase Alox15, Linoleate 13S-lipoxygenase, LOG15 |
| Location | Cytoplasm, Cell membrane |
| Accession | P16050 |
| Clone Number | S-R308 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| ICC | 1:500 | null |
| ICFCM | 1:500 | null |
Background
ALOX15 (also termed arachidonate 15-lipoxygenase, 15-lipoxygenase-1, 15-LO-1, 15-LOX-1) is, like other lipoxygenases, a seminal enzyme in the metabolism of polyunsaturated fatty acids to a wide range of physiologically and pathologically important products. By metabolizing the ω-3 polyunsaturated fatty acids, eicosapentaenoic acid and docosahexaenoic acid, into 17-HpDHA, 17-HDHA, and the resolvins and protectins, ALOX15's metabolic action is thought to be one mechanism by which dietary ω-3 polyunsaturated fatty acids, particularly fish oil, act to ameliorate inflammation, inflammation-related diseases, and certain cancers.
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