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Description
alpha smooth muscle Actin Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-132-63)Product Specification Host Rabbit Antigen alpha smooth muscle Actin (SMA) Synonyms Alpha actin 2,ACTA2 Immunogen Synthetic Peptide Location Cytoplasm, Cytoskeleton Accession P62736 Clone Number SDT 132 63 Antibody Type Recombinant mAb Application ICC, ICFCM, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300 Stability & Storage
Product Specification
| Host | Rabbit |
| Antigen | alpha smooth muscle Actin (SMA) |
| Synonyms | Alpha-actin-2,ACTA2 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cytoskeleton |
| Accession | P62736 |
| Clone Number | SDT-132-63 |
| Antibody Type | Recombinant mAb |
| Application | ICC, ICFCM, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| IF | 1:1000 | null |
| ICFCM | 1:200 | null |
| ICC | 1:1000 | null |
Background
α-smooth muscle actin, encoded by ACTA2, is expressed in abundance in vascular smooth muscle, comprising 50–70% of total actin, with the remainder composed of β-cytoplasmic and γ-actins. Whereas α-smooth muscle expression is normally restricted to smooth muscle cells, it can also be expressed in nonmuscle cells, most notably myofibroblasts that use cell traction forces to remodel extracellular matrix.
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