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Description
DPP4/CD26 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms ADABP, ADCP2, DPPIV, TP103 Accession P27487 Amino Acid Sequence Asn29 Pro766, with N hIgG1 Fc Expression System HEK293 Molecular Weight 105 120 kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability &
Product Specification
| Species | Human |
| Synonyms | ADABP, ADCP2, DPPIV, TP103 |
| Accession | P27487 |
| Amino Acid Sequence | Asn29-Pro766, with N-hIgG1 Fc |
| Expression System | HEK293 |
| Molecular Weight | 105-120 kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Klemann C. et al. (2016) Cut to the chase: a review of CD26/dipeptidyl peptidase-4’s (DPP4) entanglement in the immune system. Clin Exp Immunol. 185(1): 1-21. 2、Mortier A. et al. (2016) CD26/dipeptidylpeptidase IV—chemokine interactions: double-edged regulation of inflammation and tumor biologyJ. Leukoc Biol. 99(6): 955-969. 3、Rohrborn D. et al. (2014) Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells. FEBS Lett. 588(21): 3870-3877. 4、Enz N. et al. (2019) CD26/DPP4 - a potential biomarker and target for cancer therapy. Pharmacol Therapeiut. 198: 135-159. |
Background
Dipeptidyl peptidase 4 (DPPIV, also known as CD26) is an approximately 110 kDa serine exopeptidase that releases Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of oligo- and polypeptides. Mature human DPPIV consists of a 6 amino acid (aa) cytoplasmic tail, a 22 aa transmembrane segment, and a 738 aa extracellular domain (ECD) that contains the catalytic active site. DPPIV is expressed as a noncovalent homodimer on the surface of epithelial cells, endothelial cells, and activated lymphocytes, and it can be released by MMP mediated shedding. It regulates immune and endocrine function through the cleavage of multiple chemokines, growth factors, and peptide hormones. CD26/dipeptidyl peptidase (DPP) 4 is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express CD26/DPP4 to a variable extent. By cleaving dipeptides from peptides with a proline or alanine in the penultimate position at the N-terminus, it regulates the activity of incretin hormones, chemokines and many other peptides. Due to these effects and interactions with other molecules, a tumor promoting or suppressing role can be attributed to CD26/DPP4. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
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4.1 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
100% worth the money
Size: 16'' x 43'', Size: 16'' x 43''
Great product. They look good and function well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 6, 2026
★★★★★ 5
Cheaper than the supply house.
Size: 42'' x 28''
I used black pipe similar to this to build some shelves in my man cave. I went looking to build a studio desk and found that Lowe's wanted $8 per floor flange (~$96 just for flanges and not including the pipe, tees, or the other fittings). Even supply house dot com wanted $4 per flange (~$48, but was still missing the other parts AND they didn't offer them because of supply chain issues). For about $65, this was a great buy. Yes everything is greasy. This will be the case regardless of where you buy it. I used some gloves, shop towels, and acetone and it cleaned up easily. For a top, I used a pre-made countertop from Lowe's (~$100) and a 1x4 piece of poplar I had sitting around.
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Reviewed in the United States on January 7, 2023
★★★★★ 4
Pipes don't assemble square, nice stand though.
Size: 42'' x 28''
These arent standard SCH40 pipe for starters. Significantly lighter. Easier to move around and sturdy enough to support a table, but this isnt pipe. As such, when I threaded it together, it wasn't square. I was able to flatten it mostly, but I had to use a clamp to bend the assembled piping to sguare so it would attach to the table runners. It's fine, but it surprised me. It looks nice, and it provides plenty of support for the table. All good. Several folks complained that the pipes are oily. They are supposed to be to prevent rust. I wiped them down with a few cleaner wipes, and they are fine. Be aware that this doesn't come with instructions or the wood screws you may need for your table top.
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Reviewed in the United States on February 8, 2023
★★★★★ 5
Sturdy & Tuff going on 6 months +
Size: 28'' x 14'', Size: 28'' x 14''
I mounted a thick heavy piece of butcher block to these legs and made a desk. Easy to assemble and install. Mark the holes, pre drill pilot holes and screw them in. I will say I knew they were going to be greasy out of the box. They grease them in the factory to prevent rusting so just wipe them off with an old rag and your good to go. They haven’t felt wobbly or anything like that and butcher block is pretty heavy. I have to say I love them and much cheaper than buying from the hardware store. I’m thinking about building a second one and I would definitely purchase again. Again very sturdy and easy to assemble. People mad about the grease need to realize it’s done as an anti rust measure and it wipes right off and zero rust thus far.
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Reviewed in the United States on March 6, 2023
★★★★★ 1
Absolutely not.
Size: 28'' x 14'', Size: 28'' x 14''
Truly terrible product. If you're wanting extreme DIY, aka cleaning it repeatedly, no instructions, and still not impressive quality, this is the item for you.
After much time spent trying to remove the nasty oily substance all over the pipes and some sort of weird dirt coming out of the pipes as well, it still hadn't fully come off. When cleaning off the grease, it also took the color off of the item and created a weird, lined look on the pipes, like it was some legit oil rubbed crud on it, instead of paint to look oil rubbed.
There is also what appears to be rust on some of the pieces. If someone actually wanted to use the desk and actually bumped into one of the pipes, it would without doubt leave oily residue on clothing. Pictures included of the box without pieces in it as it beautifully captures just how much crud was all over.
100% do not recommend and would give zero stars if it was allowed, but alas.
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Reviewed in the United States on August 4, 2025
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