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Description
ErbB3 Recombinant Rabbit mAb,PBS Only (SDT-991-73-2)Product Specification Host Rabbit Antigen ErbB3 Synonyms Receptor tyrosine protein kinase erbB 3, Proto oncogene like protein c ErbB 3, Tyrosine kinase type cell surface receptor HER3, HER3 Immunogen Recombinant Protein Location Cell membrane Accession P21860 Clone Number SDT 991 73 2 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | ErbB3 |
| Synonyms | Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, HER3 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P21860 |
| Clone Number | SDT-991-73-2 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:200-1:500 |
Background
HER3/ERBB3 is a member of the family of ERBB receptor protein tyrosine kinase family, but lacks tyrosine kinase activity. The phosphoric acidization of ERBB3 depends on the combination of other ERBB tyrosine kinase. When combined with ligands, an heterodimers is formed between ERBB3 and other ERBB proteins. ERBB3 is widely expressed in human adult tissues, including cells of the gastrointestinal, urinary, respiratory, reproductive tracts, skin, endocrine and nervous systems. ERBB3 is highly expressed in many cancer cells, such as breast, ovarian, lung, colorectal, melanoma, head and neck, cervical and prostate cancers.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
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