SKU: 42769758367

Leptin Protein, Human

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Description

Leptin Protein, HumanProduct Specification Species Human Synonyms LEPD, Obesity protein (OB), LEP Accession P41159 Amino Acid Sequence Val22 Cys167 Expression System E. coli Molecular Weight Approximately 16. 0 kDa, a single non glycosylated polypeptide chain containing 146 amino acids. Purity 97% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 50 mM PB, with 0. 02% (v v) Tween 20, pH 3. 5. Reconstitution

Product Specification


Species Human
Synonyms LEPD, Obesity protein (OB), LEP
Accession P41159
Amino Acid Sequence

Val22-Cys167

Expression System E.coli
Molecular Weight Approximately 16.0 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.
Purity >97% by SDS-PAGE or HPLC.
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

50 mM PB, with 0.02% (v/v) Tween-20, pH 3.5.

Reconstitution Before use this product, please read the direction below carefully.
This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
Reconstitute in a sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
Stability & Storage

For long term storage, the product should be stored ≤ -20℃.
Please avoid repeated freeze-thaw cycles after reconstitution.
12 months from date of receipt, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution.
3 months, -20 to -70℃ under sterile conditions after reconstitution.

Background

Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. The absence of leptin (or its receptor) leads to uncontrolled food intake and resulting obesity. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Human Leptin is a 16.0kDa protein containing 146 amino acid residues.

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SKU: 42769758367

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4.8 ★★★★★
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Verified Purchase
buckzmom
Omaha, US
★★★★★ 5
It's a Hit a Our House!
Size: Large
My strong chewer is still ..... Well, going strong! He loves his new crackle ball. He enjoys the new sound, the bounce back feeling in his jaws when chews. Mom is happy that pup hasn't put a dent in the toy yet! Price was more than reasonable too. We give it 5 Paws Up!
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Reviewed in the United States on May 25, 2026
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Verified Purchase
Lisa
Whiting, US
★★★★★ 4
Medium size preferred.
Size: Large
I purchased both the large 4" and the medium 3" balls. My 80 lbs German shepherd much prefers the medium size. Show loves to play fetch with it and its lasted well!
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Reviewed in the United States on May 10, 2026
H
Verified Purchase
Hilde’s Mom
San Leandro, US
★★★★★ 5
The Piglet turned my old dog EVIL!
This little piglet turned my old lady into a monster. She normally plays with the full-sized version, but I saw this little guy for like 75% off, so I thought, “What the heck! Let’s give the piglet a try!” Friends, it made my 14-year-old fuzzy girl CRAZY! I can’t attest to its durability because my girl’s teeth aren’t as sharp as they used to be, but I suspect a few years ago she would have torn it to pieces in a matter of minutes. It’s not incredibly thick, but it is nice and soft for her old lady mouth, and I like that it’s a safe toy to throw around the house because it’s small and relatively harmless. The piglet continues to bring her joy with its squeaking, and it’s just adorable to watch her become Evil Dog when I try to take it away from her! (I almost lost a finger!) I wouldn’t pay full price for it, but on super sale, it’s a real bargain.
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Reviewed in the United States on September 29, 2025
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Verified Purchase
Amy
Boise, US
★★★★★ 5
Purchased multiple times for different dogs. LOVE the pigs
These little piggies have been a staple in my house for years for3 dogs. I ordered the large pigs for my Great Dane and the smaller ones for my Black and Tan (yes he is a rotten house dog) and the Norfolk Terrier. Different personalities but they all love the pigs! They last FOREVER. My dogs make it a mission to find and destroy the squeakers in other toys, but the pigs give them a run for their money and hours of play time. Definitely recommend for all breeds - remember they also come in a larger size
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Reviewed in the United States on October 19, 2025
A
Verified Purchase
Amazon Customer
West Palm Beach, US
★★★★★ 5
My Dog's Favorite Toy
When my small poodle mix was rehomed to me, he came with many toys. One of them was this latex squeaky toy. It is his absolute favorite toy and I've bought several more so I have them on hand if anything happens to the original Polka-dot Pig. Amazingly, my dog is a chewer but has never used this toy to chew on - only to play with. He will sometimes play by himself with it, but usually it's a robust game of indoor fetch (he doesn't fetch outside, go figure). An added bonus is that with the inhale of air, the toy makes a different squeak that inspires my dog to howl. It's a riot. People should know that this toy is LOUD and the smaller size does not grunt, it squeaks. Another bonus is that it squeaks with the slightest touch - the dog doesn't have to find the squeaker in the toy, the whole toy is the squeaker. Oh, and it also bounces erratically, which is fun for the dog. This household will never be without Polka-dot Pig.
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Reviewed in the United States on September 8, 2023

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