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Description
cAMP Recombinant Mouse mAbProduct Specification Host Mouse Antigen cAMP Clone Number cAMP RW282RL282 Antibody Type Recombinant mAb Isotype IgG Application ELISA Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as supplied Dilution application dilution species ELISA 1: 5000 1: 10000 Background Cyclic adenosine
Product Specification
| Host | Mouse |
| Antigen | cAMP |
| Clone Number | cAMP-RW282；RL282 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | ELISA |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 1:5000-1:10000 | / |
Background
Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that plays a fundamental role in transducing extracellular signals into intracellular physiological responses. It is synthesized from ATP by adenylyl cyclase enzymes upon activation of G-protein-coupled receptors (GPCRs) and is degraded by phosphodiesterases (PDEs). The intracellular levels of cAMP directly regulate critical cellular processes, including metabolism, gene transcription, ion channel activity, cell proliferation, and apoptosis, primarily through the activation of protein kinase A (PKA) and the Exchange Protein directly Activated by cAMP (EPAC).
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