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Description
CD19 Recombinant Rabbit mAb (SDT-164-33)Product Specification Host Rabbit Antigen CD19 Synonyms B lymphocyte antigen CD19; LE CD19; B lymphocyte surface antigen B4; Differentiation antigen CD19; T cell surface antigen Leu 12 Immunogen Synthetic Peptide Location Cell membrane Accession P15391 Clone Number SDT 164 33 Antibody Type Recombinant mAb Application WB, IHC P, IF Reactivity Hu Purification Protein A Concentration 0. 25 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | CD19 |
| Synonyms | B-lymphocyte antigen CD19; LE-CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P15391 |
| Clone Number | SDT-164-33 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied. |
Dilution
| application | dilution | species |
| WB | 1:500 | |
| IHC | 1:1000 | |
| IF | 1:50 |
Background
The CD19 antigen plays an important role in clinical oncology. In normal cells, it is the most ubiquitously expressed protein in the B lymphocyte lineage. CD19 expression is induced at the point of B lineage commitment during the differentiation of the hematopoietic stem cell, and its expression continues through preB and mature B cell differentiation until it is finally down-regulated during terminal differentiation into plasma cells. CD19 expression is maintained in B-lineage cells that have undergone neoplastic transformation, and therefore CD19 is useful in diagnosis of leukemias and lymphomas using monoclonal antibodies (mAbs) and flow cytometry [PMID: 8528044].
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