SKU: 45951046873

Tau (phospho T181) Mouse mAb (SDT-200-9)

Sale price$375.75 Regular price$417.50
Save 10%

Pay in installments of $104.38 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 11 - Aug 16

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Tau (phospho T181) Mouse mAb (SDT-200-9)Product Specification Host Mouse Antigen Tau (phospho T181) Synonyms p Tau181, phospho T181 Immunogen Synthetic Peptide Accession P10636 Clone Number SDT 200 9 Antibody Type Mouse mAb Isotype IgG1,k Application Sandwich ELISA Reactivity Hu, Ms Predicted Reactivity Hu, Ms Cross Reactivity Does not recognize total Tau Purification Protein G Concentration 5 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS

Product Specification


Host Mouse
Antigen Tau (phospho T181)
Synonyms p-Tau181, phospho T181
Immunogen Synthetic Peptide
Accession P10636
Clone Number SDT-200-9
Antibody Type Mouse mAb
Isotype IgG1,k
Application Sandwich ELISA
Reactivity Hu, Ms
Predicted Reactivity Hu, Ms
Cross Reactivity Does not recognize total Tau
Purification Protein G
Concentration 5 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Dilution


application dilution species
Sandwich ELISA N/A

Background

Accumulation of intraneuronal neurofibrillary tangles (NFTs) containing paired helical filaments (PHFs) of the microtubule-associated protein tau is one of the defining neuropathological hallmarks of Alzheimer’s disease (AD). The tau protein has an N-terminal projection domain, a proline-rich region, a repeat region, and a C-terminal domain, with multiple potential phosphorylation sites along all regions. Studies using preparations of PHFs and immunohistochemical staining of postmortem brain tissue with specific tau antibodies established that PHF tau is hyperphosphorylated. High levels of p-tau and total tau (t-tau) have consistently been found in cerebrospinal fluid (CSF) of AD patients. However, while CSF t-tau is considered a non-specific biomarker of neuronal injury, p-tau may reflect AD-related tau pathology in the brain. The vast majority of CSF studies have used immunoassays detecting tau phosphorylated at threonine (Thr) 181 (p-tau181). During the last 2 decades, CSF p-tau181 together with total tau (t-tau) and amyloid-β 42 (Aβ42) have been extensively validated as biomarkers of AD and are currently widely used as diagnostic criteria in research studies, in clinical practice in some countries, and for patient selection in clinical trials. CSF p-tau181 (alone or in combination with Aβ42) accurately differentiates AD from controls and predicts cognitive decline in preclinical and prodromal disease stages. CSF p-tau181 levels are higher in AD compared with other tauopathies including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) and, hence, CSF p-tau181 has also been proven useful in differential diagnosis of dementia.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 45951046873

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.1 ★★★★★
Based on 29 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
M
Verified Purchase
Marty
Whiting, US
★★★★★ 4
Durable dog toy
Solid toy for Malinois
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 26, 2026
D
Verified Purchase
Debi Mason
Louisville, US
★★★★★ 5
Extremely Durable
This is truely for heavy chewers. Both my bully mixes have chewed through every bone/ball including Kong. They have had these for about 6 months and they are hardly worn. The dogs love chewing on them too. I wish they came in flavors.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
C
Verified Purchase
Cherrieleneay
Phoenix, US
★★★★★ 5
Must have toy
Found out the hard way my sweet little shy rescue pup can chew through any toy in under 5 min. If it says indescribable they have never met her....until this toy. It has been almost two weeks now. She loves this thing and you cannot tell she has even tried to destroy it. If she does manage to somehow I am instantly buying another. This thing is awesome, a must have for super cheers, and she LOVES it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 8, 2026
K
Verified Purchase
KA
Port Orchard, US
★★★★★ 1
Not even close to "virtually indestructible" as described.
Within an hour of receiving this K9 Chew Stick, our 55lb Staffordshire Terrier began chewing pieces off the top of toy. Initially, we were happy to see that our dog enjoyed the chew toy, and it appeared to be durable. For the high cost of this toy, it is very disappointing that pieces can start coming off that quickly. Luckily, our dog wasn't swallowing the pieces, which can easily lodge in their intestines. If your dog is NOT an aggressive/determined chewer or they are happy with chewing for very short periods of time, this toy might be okay for them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
T
Verified Purchase
thomas nation
Cuba, US
★★★★★ 5
Durable for Heavy Chewing Rottweiler
Fit for Rottweiler, indestructible and ordered the Y stick from them as well! Lasted longer than any other toy I’ve given her. Kong who?
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 4, 2026

recommand products