SKU: 47020047701

Biotin Armenian hamster Anti-Mouse CD11c Antibody (S-R518)

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Description

Biotin Armenian hamster Anti-Mouse CD11c Antibody (S-R518)Product Specification Host Armenian hamster Antigen Mouse CD11c Synonyms Integrin alpha X; CD11 antigen like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax Location Membrane Accession Q9QXH4 Clone Number S R518 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation

Product Specification


Host Armenian hamster
Antigen Mouse CD11c
Synonyms Integrin alpha-X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax
Location Membrane
Accession Q9QXH4
Clone Number S-R518
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD11c, also known as the integrin alpha X chain, is a type I transmembrane glycoprotein and a component of the complement receptor 4 (CR4). CD11c is primarily expressed on myeloid dendritic cells (DCs) and acts as a positive regulator in the adhesion, migration, antigen recognition, and presentation processes, leading to the activation of CD4+ and CD8+ T cells. It is not only expressed on dendritic cells but also on other immune cells such as alveolar macrophages and cells in adipose tissue. In humans, monocytes and dendritic cells can both express CD11c. Additionally, CD11c expression has been detected in a subset of gut macrophages, neutrophils during inflammation, a small fraction of B cells (mainly in autoimmune diseases), natural killer cells, and T cell subsets. In diseased brains, activated microglia can also express CD11c. CD11c forms a heterodimer with CD18, belonging to the β2 integrin family, and together with CR3 (comprising CD11b and CD18), it is involved in cell adhesion, migration, and phagocytosis. CR3 and CR4 have overlapping ligand-binding specificities and bind to various ligands such as fibrinogen or heparin. In oncology, CD11c is an important marker for diagnosing hairy cell leukemia, acute myeloid leukemia, and some chronic lymphocytic leukemias. Furthermore, the expression of CD11c is associated with liver inflammation and microglial activation.

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SKU: 47020047701

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Killa Kam
Lowell, US
★★★★★ 5
Fixed my aches, real improvement in sleep
Size: Queen
It actually does make my bed feel better. I was skeptical, but decided to try it because our mattress isnt very old but I wake up with aches in my hips/lower back. When I got it, I thought no way this works. But it does. It goes in like a fitted sheet, super easy to put on. And I honestly havent woken up with hip or lower back aches since using it. Had it on our bed for about 2 months now. I read some people say they sleep hotter with it, but I havent noticed that at all. Temperature feels the same as without it. So glad I tried this before spending money on a mew mattress!
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Reviewed in the United States on May 27, 2026
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Sandra Walker
San Leandro, US
★★★★★ 5
Best Mattress Pad!
Size: Queen
This is the best mattress pad you are going to find anywhere and the price is actually a bargain compared to all the other mattress pads I saw in the stores or online. Thought I needed a new mattress but all I needed was this comfy cover.
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Reviewed in the United States on April 26, 2026
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Juli J. Denning
West Palm Beach, US
★★★★★ 5
Soft, comfortable and really nice.
Size: Full
This product is of really nice material. It's soft and comfortable, deep pockets and fits my bed perfectly. It's a great product, however, if you're looking for something for back support, this isn't it. It isn't for me anyway - there's no firmness to this topper at all but it is very comfortable.
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Reviewed in the United States on April 5, 2026
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Mrs. V
San Leandro, US
★★★★★ 5
COMFORTABLE AND WORTH THE MONEY
Size: Queen
Excellent mattress topper. Its thick and paired with my matress provides a high end hotel feel. I have had it for a few months and it has not lost its shape and stays in place. Worth the money. You are definitely getting what you paid for.
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Reviewed in the United States on May 26, 2026
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Pam
Los Angeles, US
★★★★★ 5
Awesome!!
Size: King
This mattress topper is like sleeping on a cloud. It is so soft and comfortable to sleep on. It stays on the mattress very nice. Great price for a very nice topper. Highly recommend
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Reviewed in the United States on March 23, 2026

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