SKU: 47100947482

Biotin Mouse Anti-Human CD141 Antibody (S-2870)

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Description

Biotin Mouse Anti-Human CD141 Antibody (S-2870)Product Specification Host Mouse Antigen CD141 Synonyms Thrombomodulin; TM; Fetomodulin; THRM; THBD Location Membrane Accession P07204 Clone Number S 2870 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt

Product Specification


Host Mouse
Antigen CD141
Synonyms Thrombomodulin; TM; Fetomodulin; THRM; THBD
Location Membrane
Accession P07204
Clone Number S-2870
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD141, also known as thrombomodulin, is a 75 kDa single-chain type I membrane glycoprotein that serves as a crucial cofactor in the protein C anticoagulant system. It is expressed on various cell types, including endothelial cells, monocytes, dendritic cells, and keratinocytes. When thrombin binds to CD141, it activates protein C, which degrades clotting factors Va and VIIIa, thereby reducing thrombin generation and preventing excessive blood coagulation. Additionally, CD141 is involved in embryonic development and atherosclerotic plaque formation. In the immune system, CD141+ dendritic cells have been shown to produce significant amounts of IFN-α in response to certain stimuli, indicating their important role in immune responses.

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Exchange/Return Notes
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SKU: 47100947482

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4.4 ★★★★★
Based on 13 reviews
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B
Verified Purchase
Bruce
Los Angeles, US
★★★★★ 4
Well made shoes.
Size: 11.5, Color: Black
Four stars because of the weight. Too heavy for my complete comfort. Also I have a narrow foot (C width) and these are too wide for me. Heavy socks make them wearable but not as comfortable as I would have liked.
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Reviewed in the United States on December 1, 2025
M
Verified Purchase
marsha
Grantham, US
★★★★★ 5
Good look
Size: 11, Color: Brown Crazy Horse
Great look.
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Reviewed in the United States on April 23, 2026
D
Verified Purchase
Dave M
Natrona Heights, US
★★★★★ 1
Something's changed at Florsheim
Size: 11.5 Wide, Color: Black
I have a pair of size 11W Florsheim Palermo loafers that have lasted over 8 years and are still soft and exceptionally comfortable. Ordered a pair of 11W Florsheim Milano on Amazon but they are too small and have a cheap plastic sole. So, ordered 11.5W Florsheim Berkley and they were way too big. Returned them and ordered 11W Berkley instead and they were also too big ... and the Berkley also has a rubber sole instead of the original leather shown in the product photos. Guess they just don't make them like they used to.
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Reviewed in the United States on May 25, 2026
C
Verified Purchase
Cliff
Whiting, US
★★★★★ 3
Beware of the Brown Crazy Horse version.
NOTE: This review is COLOR SPECIFIC and concerns the Brown Crazy Horse version of this shoe. I am a loyal Florsheim customer having purchased Florsheim Imperials in years past. They are a fine shoe. However, I have to admit complete frustration with the Florsheim Berkley Flex Penny Loafer in "Brown Crazy Horse." The photos in the listing show a shoe with gloss...a shine. The photos on the box show a shoe with shine. Don't believe the photos. "Brown Crazy Horse" is, at best a dull matte finished leather. If you want a classic penny loafer with the classic Florsheim look this is NOT the color to choose. When the shoes arrived and the shoes did not match the photo on the box, I ignorantly assumed it was merely a case of the wrong shoes in the box so I exchanged them for another pair, which was a big mistake. It is Florsheim's incorrect photo and box label that caused me the inconvenience of going through two pair and then having to return both. I would assume other colors are as pictured in their listings because I cannot imagine that every Florsheim Berkley Flex Penny Loafer is a dull matte finish. I'm sorry that I do not have photos of the dull finished shoes. You'll have to take my word for it. They are a matte finish at best.
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Reviewed in the United States on January 21, 2026
D
Verified Purchase
Dean
Omaha, US
★★★★★ 5
Just right, great quality and value (in the price)
Size: 11.5 X-Wide, Color: Burgundy
Exactly what I'd expect from a Florsheim. I'm delighted. Folks, let me share one mistake I made on my way to a good fitting pair of shoes. I ordered some in my size (I have a big foot, especially in width). I ordered what I thought I needed and it came in wide enough, but too short (the short was the surprise), but we all are told: "Manufacturers vary in their sizes not only from each other but from shoe model to shoe model." I want you to know I believe in that when it applies to clothes, especially children's and womens fashions in my life's experiences, but NOT with shoes, especially main-brand-deluxe. I ordered the next half-size up and now I have too large, how can that be? I found out when I pulled the paper stuffing out, in particular the LAST glob that extends from the middle to the toe, that it WASN'T the last glob, there was indeed a rather small glob still way down in the toe, almost pointless for this minor bit of stuffing being separate from the other, but it was. I had already innocently troubled Amazon with returns of shoes that would have fit, so I'll keep the half-size too large as a life lesson. I ordered this pair in the size I believed I was all along and viola, a good fit. What changed? When that last toe piece of paper wadding that's hard to see and even harder with a big hand to reach, the shoe fit perfectly. That's a lot of trouble because of a small piece of paper that was hard to see, but that's why I write this review for you so that you can make sure all the paper is really out when you already think it is. Amazon has been good enough not to hold me accountable and in return I'll not only repeat buy, I tell you of my experience.
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Reviewed in the United States on December 3, 2014

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