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Description
NRF2 Protein, HumanProduct Specification Species Human Synonyms Nuclear factor erythroid 2 related factor 2,erythroid derived 2 HEBP1 like 2 Accession Q16236 Amino Acid Sequence Met1 Asn605 Expression System PichiaPastoris Molecular Weight 70. 0 kDa Purity 90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH 7. 4 or 20 mM PB, 6% Trehalose, pH 7. 0. Reconstitution It is not recommended to
Product Specification
| Species | Human |
| Synonyms | Nuclear factor erythroid 2-related factor 2,erythroid derived 2 HEBP1 like 2 |
| Accession | Q16236 |
| Amino Acid Sequence | Met1-Asn605 |
| Expression System | PichiaPastoris |
| Molecular Weight |
70.0 kDa
|
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer |
PBS, pH 7.4 or 20 mM PB, 6% Trehalose, pH 7.0.
|
| Reconstitution |
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
|
| Stability & Storage |
Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is
recommended to freeze aliquots at -20°C or -80°C for extended storage. |
Background
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
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4.1 ★★★★★
Based on 22 reviews
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Product Reviews
★★★★★ 5
Profoundly challenging; I'm going back to this over and over
Format: Paperback
The remarkable growth of the early church has puzzled and challenged scholars. How did a tiny sect that attracted mainly the poor and unimportant and faced waves of persecution grow? How did they sustain their vigor and their distinctiveness such that well into the third century they were still well known for their non violence and care of the poor and downtrodden? Why did the church make baptism and membership so difficult? I've never found satisfactory answers. Kreider's exhaustively researched book did more than answer those questions. It stirred and challenged my thinking about how to "do church."
He argues, with compelling evidence, that a central conviction by the early Christians had much to do with their sustained vitality. They centered on the teachings of Jesus, in particular the sermon on the mount. They actually believed they were to live in obedience to the upside down Way of Jesus. It was this distinctive and intriguing lifestyle - Kreider uses the term "habitus" or their habitual behavior - that the church insisted upon and that attracted others. They patiently lived in community, expecting that over time, the impact of the light of their lives would "bubble up" or ferment in the lives of their neighbors.
So, rather than emphasize evangelism, the early Christians emphasized catechesis - careful formation and teaching. Only after a lengthy period of time - up to three years! - during which the prospective member was mentored and drilled in the life of Christ, was the person allowed to be baptized and take the Lord's Supper. They had to demonstrate, prove, that they were indeed genuinely living the life of Christ. Caring for the poor, sharing their resources, returning good for evil, turning the other cheek - those things had to be demonstrably evident.
Kreider ends by contrasting this patient habitus with the changing focus after Constantine. His examination of Augustine's redefinition of faithful Christian living that provided a way for Christians to both claim allegiance to Jesus' teachings yet use force and violence was both incisive and deeply saddening.
These days, most followers of Jesus do a better job of rationalizing why they can't take the Sermon on the Mount as more than platitudes. This book further challenges me, and I hope, the church at large, to actually live like Jesus! What a novel idea.
There are just a handful of books that have deeply influenced me, books that I find myself returning to again and again. The Patient Ferment is one of those books now. I hope this book becomes widely read, and even more, widely influential. May it disturb our comfort...
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Reviewed in the United States on May 8, 2017
★★★★★ 4
Insightful, balanced and thoroughly researched
Format: Kindle
I was a bit afraid that this book would somehow a attribute of the early church, postulate it as a silver bullet and then suggest it simplictically as the only solution for the modern day church. Instead I got a well balanced, finely nuanced and engagingly told narrative of the early church and the role patience was practiced, neglected and rethought by various Christian groups and bishops. The book end with an adequate invitation to think the concepts through for our own time.
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Reviewed in the United States on January 11, 2018
★★★★★ 5
Excellent
Format: Paperback
I might be as bold to say this is my favorite book on Christianity I have read to date.
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Reviewed in the United States on October 2, 2025
★★★★★ 5
Patience and Christianity
Format: Kindle
Short review: buy it
Long review:
It is incredible the simplicity of the Christians praxis in its origins, and how Saint Augustine and then Luther totally misunderstood these origins.
I can’t give you all the thoughts about this book, but here a glimpse of some ideas:
- The forgiveness between Christians is still powerful mean to live in peace and in a productive way
- The peace kiss is now forgotten, but it was a very powerful practice that maintain unity in the communities
- Women in the church were extremely important, they helped with maintain the union and share information
- The first Christian didn’t think that mission was most important than behavior, and for good reasons: talk is cheap, actions are more important.
- The testimony was noting about believe, it was about behave as a Christian, you can only access the great teachings of the New Testament once you showed with your actions that you are worthy of that.
Incredible simple, I think that is difficult to destroy religion only with reason, because religions have nothing to do with theology, is about behavior and cooperation.
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Reviewed in the United States on November 17, 2020
★★★★★ 5
Almost Persuaded
Format: Kindle
Almost thou hast persuaded me to become a pacifist. Kreider presents an outstanding survey of the Christian emphasis on patience in the first four centuries of the church. I am rethinking everything. Loved this book.
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Reviewed in the United States on November 27, 2023