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Description
ECM1 Recombinant Rabbit mAb (S-2235-35)Product Specification Host Rabbit Antigen ECM1 Synonyms Extracellular matrix protein 1; Secretory component p85; Ecm1 Immunogen Recombinant Protein Location Secreted Accession Q61508 Clone Number S 2235 35 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Ms Positive Sample C2C12, NIH 3T3, mouse liver Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40%
Product Specification
| Host | Rabbit |
| Antigen | ECM1 |
| Synonyms | Extracellular matrix protein 1; Secretory component p85; Ecm1 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | Q61508 |
| Clone Number | S-2235-35 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Ms |
| Positive Sample | C2C12, NIH/3T3, mouse liver |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms |
| ICC | 1:500 | Ms |
Background
ECM1 protein, or extracellular matrix protein 1, is a glycoprotein predominantly expressed in the extracellular matrix of various tissues. It plays a crucial role in cell adhesion, proliferation, and differentiation. ECM1 is highly expressed in tissues such as skin, placenta, and blood vessels. Its expression is regulated by several growth factors and hormones. Abnormal expression of ECM1 has been implicated in various pathological conditions, including cancer progression, where it may contribute to tumor growth and metastasis by modulating the tumor microenvironment. Additionally, ECM1 is involved in the development and maintenance of normal tissue architecture and has potential as a biomarker for certain diseases due to its specific expression patterns.
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