Pay in installments of $35.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 15 - Aug 20
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Lp-PLA2 Recombinant Rabbit mAb (SDT-972-303)Product Specification Host Rabbit Antigen Lp PLA2 Synonyms PLA2G7 Immunogen Recombinant Protein Accession Q13093 Clone Number SDT 972 303 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against Apolipoprotein A I, Apolipoprotein E Purification Protein A Concentration 2 mg ml Purity 95% by HPLC Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | Lp-PLA2 |
| Synonyms | PLA2G7 |
| Immunogen | Recombinant Protein |
| Accession | Q13093 |
| Clone Number | SDT-972-303 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross reactivity against Apolipoprotein A-I, Apolipoprotein E |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | ＞95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as plasma platelet-activating factor acetylhydrolase, is an enzyme encoded by the PLA2G7 gene and belongs to the phospholipase A2 superfamily. It is primarily associated with lipoproteins in the bloodstream and plays a crucial role in lipid metabolism and inflammation. Lp-PLA2 hydrolyzes oxidized phospholipids, such as oxidized low-density lipoprotein (oxLDL), into lysophosphatidylcholine and non-esterified fatty acids, contributing to the progression of atherosclerosis. Additionally, Lp-PLA2 (Lipoprotein-associated phospholipase A2) serves as a biomarker for vascular inflammation and atherosclerosis. It is specifically expressed in atherosclerotic plaques and associated with plaque instability. Elevated Lp-PLA2 levels independently predict increased risk of cardiovascular events (e.g., heart attack, stroke), particularly in individuals without traditional risk factors. While not diagnostic for specific diseases, it aids in risk stratification and may guide targeted preventive therapies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy