SKU: 50433947049

IL-12 R beta 1 Fc Chimera Protein, Human

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Description

IL-12 R beta 1 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms IL 12 R beta 1, IL12RB1, CD212, IL12R, IL12RB, IL 12RB1 Accession P42701 Amino Acid Sequence Cys24 Glu540, with C hIgG Fc Expression System CHO Molecular Weight 95 110kDa (Reducing) Purity 95% by SDS PAGE & >95% by SEC HPLC Endotoxin <0. 1EU g Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water

Product Specification


Species Human
Synonyms IL-12 R beta 1, IL12RB1, CD212, IL12R, IL12RB, IL-12RB1
Accession P42701
Amino Acid Sequence

Cys24-Glu540, with C-hIgG Fc

Expression System CHO
Molecular Weight

95-110kDa (Reducing)

Purity >95% by SDS-PAGE & >95% by SEC-HPLC
Endotoxin <0.1EU/μg
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, 5% trehalose, PH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Reference

1. Pérez-Martínez L, Romero L, Verdugo-Sivianes EM, Muñoz-Galván S, Rubio-Mediavilla S, Amiama-Roig A, Carnero A, Blanco JR. Role of maraviroc and/or rapamycin in the liver of IL10 KO mice with frailty syndrome. PLoS One. 2024 Jan 10;19(1): e0286201. l. (2008) Nat.
2. Chan BC, Li P, Tsang MS, Sung JC, Kwong KW, Zheng T, Hon SS, Lau CP, Ho RC, Chen F, Lau CB, Leung PC, Wong CK. Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge. and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection. J Leukoc Biol. 2024 Jan 5;115(1):177-189.

Background

IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

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Exchange/Return Notes
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SKU: 50433947049

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4.2 ★★★★★
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T
Thunderboltmysql
Phoenix, US
★★★★★ 4
Nice Suit - Light Gray Color OF Suit IS Not A Solid Light Gray, It Has Linear Designs
Size: 12, Color: Light Grey, Size: 12, Color: Light Grey
I had purchased this polyester and linen blend suit for my son, in size 12Y for him in the color light gray. The color of the suit depicted in the advertisement arrived to be a bit different upon arrival. It's not a solid color light gray, it actually has small black liner lines dispersed all over the suit. The coat features a single button in the center, and there are two side pockets fairly decent sized. Unfortunately right above the pockets are red colored lineal horizontal lines. I don't think those lines are part of the coat's design, there definitely is some printing malfunction. It is hard to see in the pictures advertised, you can see it in the pictures and video I have posted clearly. The material of the suit is fairly acceptable, actually better than expected. The child can actually wear it multiple times for various occasions. The suit emits grace along with acceptable stitching in every apparel along with the bowtie. The suit did arrive in a slide bag all folded up, so there were a number of wrinkles especially on the coat, its as if it had lost its shape. I will definitely need to steam iron it before it will be worn. Just like the coat has pockets the tailored pants also have two side pockets, and belt loops in case need of belt if the pants are loose. I'm actually glad I had ordered two sizes up because compared to his current measurements the suit is big on, especially the pants waist and length. I had measured the suit myself and below are the measurements. Pants Waist - 15.25 Inches Pants Length - 35.75 Inches Pant's Inseam 25 Inches Coat's Length - 24.5 Inches Coat's Shoulders - About 14.5 Inches Coat's Sleeve Length - 22 Inches Coat's Chest - 15.5 Inches In addition to the suit, I also received a solid colored light gray, bowtie. The bowtie has an adjustable strap, so you can set the bowtie to your comfort in the collar. You can wear it along the suit or without it if needed to match with something and still manage to look a show topper!. The coat has nice shoulder padding therefore it sits across the shoulders nicely having it hold its shape and style. Overall it's not a bad purchase, suits like these always come in handy for a unexpected or expected events. I'm glad I had purchased this suit I'm sure it'll come to use one day.
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Reviewed in the United States on March 10, 2026
A
Verified Purchase
Aletha
Massapequa, US
★★★★★ 5
Great Suit!
Size: 5, Color: Sky Blue
It fit well and looked very nice on my son
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Reviewed in the United States on April 17, 2026
C
Coreen Selmon
Charlottesville, US
★★★★★ 5
Adorable & Stylish Suit
Size: 4, Color: Light Grey
This suit is perfect for special occasions! The linen fabric is lightweight and breathable, great for warmer weather. The slim fit looks sharp, and the light grey color is classy. Comfortable for kids to wear and ideal for weddings or events!
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Reviewed in the United States on April 13, 2026
T
Teacher Lady
Chelsea, US
★★★★★ 5
GQ KIDS...For the love of being FLY!
Size: 8, Color: Sky Blue
I am highly suggesting this suit for purchase because the color alone is a standout and will have people asking where did you get the suit from? The length of the bowtie is adjustable, the color is bright and lively, the fabric is pure quality. You can run a hot iron over it or a steamer to get the fold lines out of it from how it was packaged, but it seems that even if you just hung it up in the bathroom while running a hot shower, the wrinkling would drop. I think the purchase price is good for all that you get which is a quality blazer, great slacks and a bowtie. It's a one stop shop for a graduation event, dinner, a formal party or even a photoshoot. My nephew wears a size 7 or 6-8, so I ordered a size 8 to be safe and it fits nicely.
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Reviewed in the United States on February 25, 2026
A
Amazon Customer
West Palm Beach, US
★★★★★ 4
Cute sky blue linen suit for toddler!
Size: 3, Color: Sky Blue, Size: 3, Color: Sky Blue
I got this Trasign Kids Linen Suit in sky blue for my 2 year old, thinking my wife said “blue” (turns out she meant navy or something darker 😅). I actually really like the light, airy sky blue. It’s fresh, summery, and looks adorable on him for photos or special occasions. My wife? Not so much. She immediately said “baby blue ugly” 😅😅 On the plus side: • Soft fabric – linen blend feels gentle and breathable on little skin, no itchiness or stiffness. • Nicely packaged – arrived with very little wrinkling (barely needed steaming), which is a win for linen. • Good fit for a toddler – true to size, easy to button, and the shorts/pants have adjustable waist for growing kids. • Looks sharp once on – the set gives that classic little gentleman vibe without feeling over the top. It’s a quality piece overall, just a classic case of “what one spouse loves, the other doesn’t” on the color. If sky blue works for your family (or you’re shopping solo like me 🤣), it’s a solid buy.
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Reviewed in the United States on February 22, 2026

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