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Description
KGF/FGF-7 Protein, MouseProduct Specification Species Mouse Antigen KGF FGF 7 Synonyms Heparin binding growth factor 7 (HBGF 7), Keratinocyte growth factor (KGF) Accession P36363 Amino Acid Sequence Cys32 Thr194 Expression System E. coli Molecular Weight 20kDa (Reducing) Purity 95% by SDS PAGE&HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to
Product Specification
| Species | Mouse |
| Antigen | KGF/FGF-7 |
| Synonyms | Heparin-binding growth factor 7 (HBGF-7), Keratinocyte growth factor (KGF) |
| Accession | P36363 |
| Amino Acid Sequence | Cys32-Thr194 |
| Expression System | E.coli |
| Molecular Weight | 20kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE&HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.MacDonald KP, Hill GR. Keratinocyte Growth Factor (KGF) in hematology and oncology. Curr Pharm Des. 2002;8(5):395-403. |
Background
Keratinocyte growth factor (KGF), also known Fibroblast growth factor 7 (FGF-7) is a member of the fibroblast growth factor (FGF) family, and plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. KGF is also a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblast and endothelial cells. Studies of mouse and rat homologous protein implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.
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