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Description
FCER1A/FcεRIα Recombinant Rabbit mAb (S-1697-174)Product Specification Host Rabbit Antigen FCER1A FcRI Synonyms High affinity immunoglobulin epsilon receptor subunit alpha; Fc epsilon RI alpha (FcERI); IgE Fc receptor subunit alpha; FCE1A Immunogen Recombinant Protein Location Cell membrane Accession P12319 Clone Number S 1697 174 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample KU812 Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | FCER1A/FcεRIα |
| Synonyms | High affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha (FcERI); IgE Fc receptor subunit alpha; FCE1A |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P12319 |
| Clone Number | S-1697-174 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | KU812 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:50 | Hu |
| ICC | 1:500 | Hu |
Background
FcεRIα (Fc epsilon receptor I alpha) is a type I transmembrane glycoprotein encoded by the FCER1A gene, which belongs to the immunoglobulin gene superfamily. It is a critical component of the high-affinity IgE receptor (FcεRI) complex, responsible for binding the Fc region of IgE antibodies with high affinity. This receptor complex is primarily expressed on mast cells and basophils, and to a lesser extent on some monocytes, Langerhans cells, dendritic cells, and eosinophils from allergic donors. Upon allergen binding to IgE, FcεRIα triggers cellular activation, leading to the release of mediators such as histamine and cytokines, which drive allergic responses and contribute to anti-parasite immunity.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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