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Description
SR-B2/LIMPII Fc Chimera Protein, HumanProduct Specification Species Human Synonyms SR B2, SCARB2, CD36L2, LIMP2, LIMPII Accession Q14108 Amino Acid Sequence Arg27 Thr432, with C terminal human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | SR-B2, SCARB2, CD36L2, LIMP2, LIMPII |
| Accession | Q14108 |
| Amino Acid Sequence | Arg27-Thr432, with C-terminal human IgG1 Fc RVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 87-107kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Neculai D. et al. (2013) Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature. 504: 172-176. |
Background
LIMPII (Lysosomal Integral Membrane Protein II), also known as LPG85 (85 kDa lysosomal membrane sialoglycoprotein) and as CD36 antigen-like 2 (CD36L2), is a major lysosomal membrane protein. LIMP-II is a type-III protein that traverses the membrane twice, with an N-terminal transmembrane anchor as a result of an uncleaved signal peptide and a second membrane spanning region near the C-terminus, followed by a 20 amino acid cytoplasmic tail. LIMPII is currently known to be a member of a superfamily of scavenger receptor proteins (class B), which also includes scavenger receptor (SR)-B1 and SR-B3. These three proteins share their structure, which comprises two transmembrane domains, a relatively large extracellular domain, and both the amino and carboxyl termini located within the cytoplasm. LIMPII as the mannose-6-phosphate- independent trafficking receptor for beta-glucocerebrosidase.
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4.1 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 4
Works Great
Color: Black
Got this for my office desk to keep everything arranged and the valet tray works out perfectly. The leather is holding up nicely, and the black color looks great on my desk. Everything fits nicely, and the little door on top swings with ease.
The inner lining has a nice material thought it either wasn't fit right to the boxes, or it has delaminated so on some of the longer edges, I need to reglue them back to the sides. Once I do that, it'll be perfect.
If the manufacturer is reading this review, please take a look at the adhesive used. Other than that it is beautiful and recommend.
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Reviewed in the United States on January 16, 2025
★★★★★ 5
Bedroom organization
Color: Black
A great asset for keeping the inside of your nightstand organized. Looks great!!
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Reviewed in the United States on May 29, 2026
★★★★★ 5
BUY THIS!
Color: Black
Got this as a gift for my stepdad- he loves it!
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Reviewed in the United States on February 1, 2026
★★★★★ 3
Not the quality I expected
Color: Brown
Good but not the quality I expected
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Reviewed in the United States on December 27, 2025
★★★★★ 5
Perfect size, high quality, very useful
I love this organizer. It is perfect for the products that I have. The back compartment is deeper, as the right drawer only goes back 2 sections. That is for taller items. The smaller drawers are perfect for small pallets, products in tubes and small containers, etc. It works just great for me. It is very sturdy and not too big. A perfect size for my counter. Highly recommend.
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Reviewed in the United States on July 8, 2024
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