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Description
FOXC1 Recombinant Rabbit mAb (S-1607-142)Product Specification Host Rabbit Antigen FOXC1 Synonyms Forkhead box protein C1; Forkhead related protein FKHL7; Forkhead related transcription factor 3 (FREAC 3); FKHL7; FREAC3 Immunogen Synthetic Peptide Location Nucleus Accession Q12948 Clone Number S 1607 142 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Positive Sample HeLa, LoVo, NIH 3T3, C6 Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | FOXC1 |
| Synonyms | Forkhead box protein C1; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3 (FREAC-3); FKHL7; FREAC3 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q12948 |
| Clone Number | S-1607-142 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, LoVo, NIH/3T3, C6 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu, Ms, Rt |
| IHC-P | 1:250 | Hu, Ms, Rt |
| ICC | 1:100 | Hu |
Background
FOXC1 is a 553-amino-acid forkhead/winged-helix transcription factor encoded by the single-exon gene on 6p25 that orchestrates embryogenesis, ocular, cardiovascular, renal, cerebellar, and skeletal development by binding DNA through its conserved forkhead domain to regulate target genes; dosage-sensitive FOXC1 expression is essential, as mutations or copy-number alterations produce Axenfeld–Rieger syndrome with anterior-segment eye malformations and secondary glaucoma, while in cancer FOXC1 drives epithelial–mesenchymal transition, metastasis, and stem-cell self-renewal via pathways such as STI-1/PrPC or DNMT3B-mediated DNA methylation, and during bone formation it partners with GATA4 to control Runx2-dependent osteoblast differentiation .
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4.2 ★★★★★
Based on 18 reviews
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Product Reviews
★★★★★ 5
helped treat my sore neck
Color: White-cooling Basic, Size: Camping Pillow(Pack of 1)
This pillow — after dialing in the right amount of shredded foam — has greatly helped my sore neck. Initially, I had to remove some foam. Then I gradually added foam until it reached optimum comfort and support.
It is also CPAP-friendly — especially when I position my head near the pillow's edge. (I am a left-side sleeper.)
I like the travel size because I use a bulky hugging pillow to ease stress on my shoulder and elbow. That makes my side of the bed feel cramped if using a larger head pillow. A smaller pillow is easy to flip end-to-end in the middle of the night.
I have spent lots of money on pillows over the years, but this is the best I've ever had for relieving [1] neck pain and [2] CPAP mask seal problems. Very comfortable, supportive, and affordable.
I did not notice any unpleasant smell — and I am usually sensitive to that kind of thing.
Would highly recommend.
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Reviewed in the United States on May 7, 2026
★★★★★ 5
Love them!
Color: White-cooling Basic, Size: Queen(Pack of 2)
Love them! After 10 years with our MyPillows, they finally lost their fluff. The reviews I read of the MyPillows of today were not good; they didn’t have as much filling as they used to. These pillows remind me of how fluffy our new MyPillows were 10 years ago!! You sink right into them and can mush them however and they stay. These are way cheaper than the Coop and it’s the same concept; add or remove the filling as needed. The cooling side is a huge plus too! You won’t be disappointed with these pillows!
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Great pillow, but the cooling effect depends on the cover
Color: Blue-ice Plus, Size: King(Pack of 2)
I really like this pillow overall. It’s comfortable, supportive, and feels well made. When you use it without a pillowcase, it definitely feels cool to the touch and does what it claims in terms of that initial cooling sensation.
However, once you put a pillowcase on it, you can’t really feel the cooling effect anymore. I’ve tried multiple different pillowcases made from different materials, and none of them really let that cool feeling come through.
That said, I still love the pillow itself. It’s comfortable and supportive enough that I’m keeping it. Just keep in mind that the cooling feature works best without a cover, which isn’t ideal for everyone.
Overall, a good pillow — just manage expectations about the cooling effect once it’s covered.
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Reviewed in the United States on February 17, 2026
★★★★★ 5
Cooling and holds shape.
Color: Blue-ice Plus, Size: Queen(Pack of 2), Color: Blue-ice Plus, Size: Queen(Pack of 2)
Very nice pillow for the price is also holding up well and holding shape very cool and comfortable to the touch. Best pillow I found in a long time.
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Reviewed in the United States on April 28, 2026
★★★★★ 5
Best Pillow Ever
Color: Blue-ice Plus, Size: Queen(Pack of 2)
Best pillow ever. Although it still gets "hot", it does take longer to get "hot". I love this pillow. I was buying a new pillow almost every 3 months. Other pillows would either remain rock hard or go flat. I was concerned at first when reading the description as I though the memory foam would be big pieces. They are soft fluffy pieces. I had to remove almost half of the foam to get the pillow to what works for me. I have not had to put any filler back in. Maybe in a couple of more months I may have to put a bit more in, but it is holding it's shape and not going flat. I do fluff it every night. This helps. I am a stomach sleeper. I have bought the expensive purple pillow and hated it so much I gave it to my daughter. This QUTOOL Pillow is the best! I bought a 2 pack. Have not used the other pillow yet, but I feel I may actually go years for once without having to buy a pillow as I have the 2nd one set aside if the first one gets to a point in need replacement. I have bought Dollar Store pillows. I have bought $300 pillows. None of them even come close to this pillow and the way you can adjust this pillow for you. The pillows came in a white mesh like bag. I keep all the unused "stuffing" in this bag. I have it hanging in my closet and I just fluff the bag once a month to keep the filling fresh so it is ready if and when I need it. Coming from someone who has trouble staying asleep, neck issues, a stomach sleeper who hate those flat pillows manufacturers think stomach sleepers like but actually hate, buy this pillow. Just buy it. Best Pillow for a picky person like me. Buy 2 or more so if you have to stay at a hotel, you can take your own pillow.
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Reviewed in the United States on June 15, 2025
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