SKU: 53796727365

HRSVA (strain A2) pre-fusion glycoProtein F0 His Tag Protein

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Description

HRSVA (strain A2) pre-fusion glycoProtein F0 His Tag ProteinProduct Specification Synonyms Prefusion glycoprotein F0 pre F protein (RSV) Accession ACO83301. 1 Amino Acid Sequence Gln26 Leu513 with His Tag at the C Terminus. Some mutations are introduced to stabilize the trimeric prefusion state of RSV Fusion glycoprotein. Expression System HEK293 Molecular Weight 55 72kDa (Reducing) Purity 90% by SDS PAGE Conjugation Unconjugated Tag His Tag Physical Appearance Liquid Storage Buffer PBS, PH7. 4 Reference

Product Specification


Synonyms Prefusion glycoprotein F0/pre-F protein (RSV)
Accession ACO83301.1
Amino Acid Sequence

Gln26-Leu513 with His Tag at the C-Terminus. Some mutations are introduced to stabilize the trimeric prefusion state of RSV Fusion glycoprotein.
Expression System HEK293
Molecular Weight

55-72kDa (Reducing)
Purity ＞90% by SDS-PAGE
Conjugation Unconjugated
Tag His Tag
Physical Appearance Liquid
Storage Buffer

PBS, PH7.4
Reference

Capella C, Chaiwatpongsakorn S, Gorrell E, Risch ZA, Ye F, Mertz SE, Johnson SM, Moore-Clingenpeel M, Ramilo O, Mejias A, Peeples ME. Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection. J Infect Dis. 2017 Dec 12;216(11):1398-1406.

Background

Human respiratory syncytial virus (HRSV) is the predominant etiological agent of acute lower respiratory tract infections in infants and demonstrates capacity for recurrent infections throughout life. The RSV fusion glycoprotein (RSV F) serves as the primary target for neutralizing antibodies in human sera. As a class I viral fusion protein, RSV F is synthesized as an inactive single-chain polypeptide that undergoes trimeric assembly.Membrane fusion is mediated through an irreversible conformational rearrangement from a metastable prefusion state to a stable postfusion conformation. Both structural states present distinct epitopes recognized by neutralizing antibodies. Notably, the postfusion RSV F conformation is currently under development as a promising vaccine candidate due to its structural stability and immunogenic properties

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SKU: 53796727365

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4.7 ★★★★★
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Phillip Abreu
Charlottesville, US
★★★★★ 5
Read during irma
Format: Paperback
Hurricane irma took out my power for a couple days, I use to collect simpsons comic books so I spent the days reading them again, this is honestly one of my favorite books, it has high quality printing and I love the simpsons rendition of old fables, If your looking to start to buy comic books this one is a great beginner book.
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Reviewed in the United States on September 11, 2017
M
Verified Purchase
mwreview
Dallas, US
★★★★★ 4
"I ordered Christian fairy tales on the internet and they sent me Hans Christian Andersen ones by mistake!"---Ned Flanders
Format: Paperback
As was first done with "Simpsons Comics Hit The Road," "Simpsons Comics Get Some Fancy Book Learnin'" actually follows the theme of the title and cover art. All the comics have the Simpsons characters portraying figures in literature from Greek Mythology to Shakespeare. The longer comics are very well done but some of the shorter ones at the end fall flat. Still, I enjoyed this change of pace from the usual Simpsons comics. It offers a very clever use of characters. "Greek To Me"--Homer plays, well, Homer (the Greek poet) who tells four stories to a gathering of children. The first is "The Labors of Hercules" with Bart as Hercules. He only completed 10, but hey, 10 out of 12 is a B+ which is the best grade Bart ever got. In the second story, Homer is Hades who abducts Marge...er, Persephone...and is taken to court over it. In the third story, Selma is Medusa and Perseus (Bart) has to cut of her head or face 100 years detention. Finally, Homer tells a string of Aesop's Fables like "The Fox and the Grapes," "The Tortoise and the Hare," and--my favorite--"The Ant and the Grasshopper" where Homer is the grasshopper and Flanders is a hilarious-looking ant! There are a lot of clever lines in this one, especially Barney as Oedipus. "Pandora, Jr."--A 5-page comic with Lisa explaining the story of Pandora's Box to Maggie. Maggie doesn't learn the lesson. Fairy Tales--Ralph plays Humpty Dumpty in a 2-page short, then there are a string of Hans Christian Andersen tales that Lisa saves from the Flanders's book burning BBQ. Lisa reads the stories to Rod and Tod. There is "The Little Mermaid", "The Prince and the Pea" (featuring Smithers and Mr. Burns), "The Shadow" (featuring the Comic Book Guy), "Thumbelina", and "The Story of a Mother." My favorite is "The Ugly Duckling." I like the scene where Marge the swan takes in the ugly duckling Bart saying, "It's not like I haven't compromised before," while watching a fat Homer swan swigging beer and burping. Arabian Tales--Dunyazad (Marge) tells King Shahryar (Moe) stories to keep from being put to death. The first one is the best. Ned Flanders is Aladdin who finds a lamp containing an incompetent genie (Homer). His wishes grant him an all-you-can-eat buffet and go-go bar and an angry wife Maude brought from the dead in skeleton form. The other stories are "Apu Baba and the Four Thieves" and "Sinbart The Sailor." Shakespeare--Plays parodied are "Antony and Cleopatra," "Julius Caesar," "Henry V," "Romeo and Juliet," "The Two Gentlemen of Verona," "Richard III," "Titus Andronicus" (in Itchy and Scratchy cartoon form), and "King Lear." Most of these, in terms of punch lines, are pretty weak. Bible Stories--Bart tells Rod and Tod some Bible stories to calm them down after they find out Sunday School is canceled. The stories parodied are "The Prodigal Son," "Abraham's Sacrifice," and "Noah's Ark." These comics were, on the whole, funnier than the Shakespeare ones.
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Reviewed in the United States on December 17, 2010
D
danny boy
Lake Worth, US
★★★★★ 4
An enjoyable Simpson Comic
Format: Paperback
Now this is a fun book. It largely uses the same tv formula of irreverent humor to poke fun at the classics. The Simpsons and their extended family in Springfield play all the roles to perfection. The only thing that stops me from giving this a 5 star rating is that there are too many stories and they all seem slightly short and episodic.
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Reviewed in the United States on May 20, 2013
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Verified Purchase
Tell It
Belleville, US
★★★★★ 5
A great way to introduce the classics to your kid
Format: Paperback
I mean it. It's very funny, yet introduces a number of important stories and characters from greek mythology and the Bible right though to Shakespeare. Will be funnier when my son reads the actual stories these are based on. A whole lotta compare and contrast will ensue, I imagine. I think it will pique his interest in the classics.
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Reviewed in the United States on January 24, 2013
K
Verified Purchase
Katz
Natrona Heights, US
★★★★★ 5
Halloween treat.
Format: Paperback
Treehouse of Horror must be something special. The person receiving this got so excited and couldn't believe she got one.
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Reviewed in the United States on October 22, 2021

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