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Description
S-RMab® Keratin 18 Recombinant Rabbit mAb (SDT-012-7)Product Specification Host Rabbit Antigen Keratin 18 Synonyms Cytokeratin 18, CK 18 Immunogen Synthetic Peptide Location Cytoplasm Accession P05783 Clone Number SDT 012 7 Antibody Type Rabbit mAb Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Predicted Reactivity Cz, Or, Pr, Gor Purification Protein A Concentration 0. 05 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage
Product Specification
| Host | Rabbit |
| Antigen | Keratin 18 |
| Synonyms | Cytokeratin-18, CK-18 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P05783 |
| Clone Number | SDT-012-7 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Cz, Or, Pr, Gor |
| Purification | Protein A |
| Concentration | 0.05 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| ICC | 1:50 | |
| ICFCM | 1:50 | |
| IP | 1:25 |
Background
Cytokeratins are proteins of cytoskeletal intermediate filaments, and their main function is to enable cells to withstand mechanical stress. In humans, 20 different cytokeratin isotypes have been identified. Cytokeratins 8, 18, 19, and 20 have been associated with bladder. Cytokeratin 18 (KRT18, also called K18), found in epithelial cells, is released from hepatocytes upon death.
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