SKU: 58761598467

PAPP-A Recombinant Rabbit mAb (SDT-226-46)

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Description

PAPP-A Recombinant Rabbit mAb (SDT-226-46)Product Specification Host Rabbit Antigen PAPP A Synonyms Pappalysin 1, IGFBP 4ase Immunogen Recombinant Protein Accession Q13219 Clone Number SDT 226 46 Antibody Type Rabbit mAb Reactivity Hu Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as supplied Dilution application dilution species

Product Specification


Host Rabbit
Antigen PAPP-A
Synonyms Pappalysin-1, IGFBP-4ase
Immunogen Recombinant Protein
Accession Q13219
Clone Number SDT-226-46
Antibody Type Rabbit mAb
Reactivity Hu
Purification Protein A
Concentration 0.25 mg/ml
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:1000 null

Background

PAPP-A is a proteolytic enzyme that was discovered to increase local insulin-like growth factor (IGF) availability for receptor activation through cleavage of inhibitory IGF binding proteins (IGFBPs). Reduced IGF signaling has been associated with increased lifespan and healthspan.
Therefore, inhibition of PAPP-A represents a novel approach to indirectly decrease the availability of bioactive IGF [PMID: 28035757 IF: 8.0 Q1 ].

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SKU: 58761598467

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4.1 ★★★★★
Based on 20 reviews
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Product Reviews
C
Verified Purchase
Cheryl Thomas
Massapequa, US
★★★★★ 5
Longevity
Size: 9.5 inch
My dogs love this!! Great for aggressive chewers
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 17, 2026
A
Verified Purchase
Amazon Customer
New York, US
★★★★★ 5
My dog loves bam-bones
Size: 5.25 inch (Pack of 1)
I wasn’t sure how my dog would like this since it’s stick shaped instead of the typical Y or T shaped bones. She was apprehensive at first but eventually loved it. She’s on her second one now. They don’t last quite as long as the name-brand nylon bones but she loves them the same and they’re a better price.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2026
C
Verified Purchase
Car k.
Cuba, US
★★★★★ 4
Good product, except that dogs don’t seem interested.
Size: 5.25 inch (Pack of 1), Size: 5.25 inch (Pack of 1)
It’s a good side for 8-20lb dogs which are the size dogs I foster. So far none of my fosters have been interested in this particular toy. I’m not sure why. It seems like a quality product, that is not so hard that it will hurt teeth but, durable enough that it will last for moderate chewers. I appreciate that it had some texture for pups to work their paws and mouths around. Again, none of the dogs here have been interested yet but other than that, as far as I can tell the product is good. I’ll update if I ever get a foster that goes HAM for it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 24, 2024
S
Verified Purchase
SB
New York, US
★★★★★ 3
Ok
Size: 5.25 inch (Pack of 1)
My pups not overly interested in it. If it had some texture it would be better. The price was right though, and it gives him some variety in his toys.
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Reviewed in the United States on March 20, 2026
A
Verified Purchase
Amazon Customer
Lowell, US
★★★★★ 5
Great product
Size: 9.5 inch, Size: 9.5 inch
My baby loves it! My dog is a mega chewer and he's 72lbs. He loves to chew on this Bam-Bone and I'm happy too
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 15, 2026

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