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Description
BID Recombinant Rabbit mAb (S-R300)Product Specification Host Rabbit Antigen BID Synonyms BH3 interacting domain death agonist, p22 BID (BID) Location Cytoplasm Accession P55957 Clone Number S R300 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from
Product Specification
| Host | Rabbit |
| Antigen | BID |
| Synonyms | BH3-interacting domain death agonist, p22 BID (BID) |
| Location | Cytoplasm |
| Accession | P55957 |
| Clone Number | S-R300 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:2000 | null |
| IP | 1:50 | null |
Background
BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into organelle membranes, primarily the outer mitochondrial membrane. The expression of BID is upregulated by the tumor suppressor p53, and BID has been shown to be involved in p53-mediated apoptosis.
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