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Description
CD163 Recombinant Rabbit mAb (SDT-222-171)Product Specification Host Rabbit Antigen CD163 Synonyms M130, Hemoglobin scavenger receptor Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession Q86VB7 Clone Number SDT 222 171 Antibody Type Recombinant mAb Isotype IgG Application IHC P, FCM, IF Reactivity Hu Predicted Reactivity Pr Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | CD163 |
| Synonyms | M130, Hemoglobin scavenger receptor |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane |
| Accession | Q86VB7 |
| Clone Number | SDT-222-171 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, FCM, IF |
| Reactivity | Hu |
| Predicted Reactivity | Pr |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC | 1:500 | |
| IF | 1:200 | |
| FCM | 1:50 |
Background
CD163 is a monocyte/macrophage specific marker expressed predominantly on cells which possess strong anti-inflammatory potential. The expression of CD163 is strongly induced by anti-inflammatory mediators such as glucocorticoids and interleukin-10, while being inhibited by pro-inflammatory mediators such as interferon-gamma. CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory response [PubMed: 22038213].
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