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Description
EHMT2/G9A Recombinant Rabbit mAb (S-4200)Product Specification Host Rabbit Antigen EHMT2 G9A Synonyms Histone lysine N methyltransferase EHMT2; Euchromatic histone lysine N methyltransferase 2; HLA B associated transcript 8; Histone H3 K9 methyltransferase 3 (H3 K9 HMTase 3); Lysine N methyltransferase 1C; Protein G9a; BAT8; C6orf30; KMT1C; NG36 Location Nucleus Accession Q96KQ7 Clone Number S 4200 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF Reactivity Hu, Ms,
Product Specification
| Host | Rabbit |
| Antigen | EHMT2/G9A |
| Synonyms | Histone-lysine N-methyltransferase EHMT2; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3 (H3-K9-HMTase 3); Lysine N-methyltransferase 1C; Protein G9a; BAT8; C6orf30; KMT1C; NG36 |
| Location | Nucleus |
| Accession | Q96KQ7 |
| Clone Number | S-4200 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | MCF7, HL-60, HEK-293, HT-1080, COS-7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Mk |
| IHC-P | 1:1000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
| IF | 1:500 | Hu |
Background
EHMT2 (also called G9a) is a nuclear lysine methyltransferase that chiefly di-methylates histone H3 at lysine 9 (H3K9me2) and lysine 27 (H3K27me1/2) to establish facultative heterochromatin and transcriptionally silence target genes, and it can act either as a repressor or, through auto-methylation-dependent recruitment of cofactors such as HP1γ and p300, as a co-activator of transcription; the enzyme exists as a homodimer or heterodimer with the related GLP/EHMT1, contains an N-terminal ankyrin-repeat domain for chromatin docking and a catalytic SET domain for methyl transfer, and its dysregulation—via overexpression in diverse solid and hematologic cancers or down-regulation in addiction and neuropathic pain—alters the expression of hundreds of genes by both histone and non-histone methylation, thereby controlling embryonic development, stem-cell lineage commitment, immune-cell differentiation, synaptic remodeling, and tumorigenicity .
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4.7 ★★★★★
Based on 6 reviews
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Product Reviews
★★★★★ 5
New Fave Dermaplane
Color: Silver
Love how heavy duty this product is and that the razors are replaceable. So much better than the cheap plastic dermaplane razors.
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Reviewed in the United States on June 2, 2026
★★★★★ 5
happy
Color: Silver
great!! the blades are sharp and last much longer than disposable plastic ones
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Reviewed in the United States on May 25, 2026
★★★★★ 5
A thrilling account of survival
Format: Hardcover
The noted Holocaust author and scholar, Joshua M. Green's book, "Unstoppable" is a compelling read and the third book I have read by this gifted author. It is historically accurate and an inspirational story about Siggy Wilzig. It reads like a novel although it is a sweeping account of an Auschwitz survivor, his family and brilliance to reach great heights in business. By sheer will, wisdom and resilience, Siggy Wilzig survived the SS atrocities he was subjected to at the concentration camp.
Beautifully written with exquisite detail to Siggi's life, the reader is quickly drawn into the life of a remarkable man; from a penniless survivor to a highly successful businessman but never forgetting his life in the camps. Continually articulated in the book is Siggi's love for his Judaism as opposed to the disdain for antisemitism and Holocaust deniers.
As a society we refer to the Holocaust as a general theme. It just connotes numbers. However, more of an impact is made on the reader when it highlights the story of one human being as it relates to the Holocaust. Greene emphasizes that fact which the reader can immediately identify with. The book is written with uncommon sensitivity, breadth and depth.
Of German-Jewish descent, Siggi and his family were sent to Auschwitz in 1943. Siggi was a teenager and was subjected to unspeakable horrors. His mother was immediately sent to the gas chamber; his father was beaten to death and he lost 57 other family members from the gestapo's evil practices.
Starvation, beatings, shootings, subjected to being naked in extreme cold were normal occurrences. However, Siggi's strength of character and uncommon wisdom, he fought to survive the death camp.
After the liberation, he arrived at Ellis Island with only $240.00 in his pocket. He took several menial jobs such as shoveling snow, working in sweatshops and various traveling jobs.
As a survivor, he made 3 vows: Never to starve again, to raise healthy, productive children and to keep the Holocaust's memory alive. The reader will revel in the ways he kept those vows.
Joshua Greene clearly describes Siggi Wilzig from many aspects. He was an inspirational yet complex human being, tenacious, both personally and in business (he became the President of an oil company and built a bank) his Jewish pride, to never forget the Holocaust and uphold what is right and just.
"Unstoppable" is a must read no matter what your ethnicity might be. It is a work illustrating the unique strength of one human being in spite of the heinous crimes endured by one person if not humanity.
Lois S.
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Reviewed in the United States on December 2, 2021
★★★★★ 5
An Amazing Story of "Rags-to-Riches" and the "American Dream" at its Best
Format: Hardcover
While it is fashionable in some circles today to believe that achieving the “American Dream” of health, wealth and happiness is no longer possible, "Unstoppable" proves the contrary. Siggi Wilzig’s “rags to riches” story is all the more amazing because he came to the United States in 1947 at the age of 21 with $240 in his pocket and then began his new life as a poor immigrant shoveling snow, cleaning toilets, and selling household goods as a travelling salesman. When one considers that Siggi had already survived torture and starvation at the hands of SS guards in Auschwitz, what he was able to achieve before his death in 2003 truly deserves to be called an “astonishing journey.”
Sigi got his opportunity to achieve his American Dream in the mid-1950s, when Sol Diamond, a prominent entrepreneur in then his late 70s, sensed that his much younger friend was the right person to take control of a struggling Texas oil company in which both Diamond and Sigi owned stock. By 1964, Sigi and a small group of friends and family had accumulated enough stock in the Wilshire Oil Company of Texas to get two seats on the company’s board of directors. A year later, Sigi was the president and chief executive officer of the company as well as the chairman of the board.
By the late 1960s, Sigi had also taken over a commercial bank—the Trust Company of New Jersey—and was its chief executive officer and chairman of the board. By the early 1990s, the bank’s assets had grown from $180 million to more than $2.2 billion and it was considered the “healthiest bank” in New Jersey.
Despite never having finished junior high school, Sigi Wilzig had the instincts and drive to become a phenomenal business success—and a bigger-than-life personality in the American Jewish community. He was a world-class story-teller comedian and charmer and these character traits also were very important to his success. But when talking about his achievements, Sigi insisted that he could not have become a business success anywhere else in the world. “Only in America is such a miracle possible. Only America is the land of freedom and opportunity.” Whether this is a true statement is not the point. Rather, Sigi believed it to be true and he acted accordingly.
While Sigi certainly enjoyed financial success, he never forgot his early years in Auschwitz and this explains why his own motto for life was: “Free Men Who Forget Their Bitter Past Do Not Deserve a Bright Future.” That said, Sigi loved his fellow human beings and had great empathy for them.
Author Joshua Greene, an accomplished scholar of the Holocaust whose books have sold more than 500,000 copies, brings Sigi to life in the pages of this superb biography. Unstoppable is an inspiring story of a remarkable American. It deserves to reach a wide audience and reading it is time well spent.
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Reviewed in the United States on April 24, 2021
★★★★★ 4
an incredible life!
Format: Kindle
This is the story of the incredible life of Siggi Wilzig. While not particularly well-written, the book is inspiring & moving and as unbelievable as Laura Hillenbrand's bio of Louis Zamperini: Unbroken.
Anyone familiar with NJ Banking or Wilshire Oil will know Wilzig's name but his life story needs to be made into a movie.
He truly was unstoppable
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Reviewed in the United States on June 29, 2021
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