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Description
VSV G (ΔTM) Protein, His tagProduct Specification Synonyms Glycoprotein G Accession P0C2X0 Amino Acid Sequence Protein sequence (P0C2X0, Met17 Ser467, with C His tag)
Product Specification
| Synonyms | Glycoprotein G |
| Accession | P0C2X0 |
| Amino Acid Sequence | Protein sequence (P0C2X0, Met17-Ser467, with C-His tag) MHSSALLCCLVLLTGVRAKFTIVFPHNQKGNWKNVPSNYHYCPSSSDLNWHNDLVGTALQVKMPKSHKAIQADGWMCHASKWVTTCDFRWYGPKYITHSIRSFTPSVEQCKESIEQTKQGTWLNPGFPPQSCGYATVTDAEAAIVQVTPHHVLVDEYTGEWVDSQFINGKCSNDICPTVHNSTTWHSDYKVKGLCDSNLISMDITFFSEDGELSSLGKKGTGFRSNYFAYETGDKACKMQYCKHWGVRLPSGVWFEMADKDLFAAARFPECPEGSSISAPSQTSVDVSLIQDVERILDYSLCQETWSKIRAGLPISPVDLSYLAPKNPGTGPVFTIINGTLKYFETRYIRVDIAAPILSRMVGMISGTTTERVLWDDWAPYEDVEIGPNGVLRTSSGYKFPLYMIGHGMLDSDLHLSSKAQVFEHPHIQDAASQLPDGETLFFGDTGLSKNPIEFVEGWFSSWKSSIAS |
| Expression System | CHO Stable Cells |
| Molecular Weight | Predicted MW: 51.8 kDa Observed MW: 65 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Tag | with C-His tag |
| Physical Appearance | Liquid |
| Storage Buffer | Supplied as a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Stability & Storage | 12 months from date of receipt, -20℃ as supplied. |
Background
The VSV-G glycoprotein is a trimeric protein that forms spikes on the surface of the vesicular stomatitis virus, contributing to its structural integrity and functionality. Each monomer within the trimer is composed of a single polypeptide chain, which folds into distinct domains that facilitate its role in viral processes. In addition to its structural roles, the VSV-G glycoprotein is involved in immune evasion. It can modulate host immune responses, allowing the virus to persist and replicate within the host. The VSV-G glycoprotein has emerged as a tool in the field of gene therapy, largely due to its ability to facilitate the delivery of genetic material into target cells.
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