Pay in installments of $42.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 20 - Aug 25
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Mouse Anti-Human CD28 Antibody (S-R547)Product Specification Host Mouse Antigen CD28 Synonyms T cell specific surface glycoprotein CD28; TP44 Location Cell membrane Accession P10747 Clone Number S R547 Antibody Type Mouse mAb Isotype IgG1 Application FCM Reactivity Hu Positive Sample human peripheral blood cells Purification Protein G Concentration 0. 02mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin 300 Stability &
Product Specification
| Host | Mouse |
| Antigen | CD28 |
| Synonyms | T-cell-specific surface glycoprotein CD28; TP44 |
| Location | Cell membrane |
| Accession | P10747 |
| Clone Number | S-R547 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1 |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood cells |
| Purification | Protein G |
| Concentration | 0.02mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD28, also known as the T-cell-specific surface glycoprotein CD28, is a protein encoded by the CD28 gene in humans. It is a glycoprotein that is constitutively expressed on both resting and activated T cells. CD28 plays a crucial role in T cell activation and signaling, providing essential co-stimulatory signals required for T cell activation, proliferation, and cytokine production. It enhances the production of IL4 and IL10 in T cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation. CD28 interacts with its ligands, CD80 (B7-1) and CD86 (B7-2), which are expressed on antigen-presenting cells, to mediate the co-stimulatory signals necessary for T cell activation. This interaction is critical for the early events of T cell activation and the decision between immunity and anergy.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy