SKU: 71674245702

Mouse Anti-Human FcεRIα Antibody (S-2866)

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Description

Mouse Anti-Human FcεRIα Antibody (S-2866)Product Specification Host Mouse Antigen FcRI Synonyms High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc gamma RI (FcRI); Fc gamma RIA (FcgammaRIa); CD64; FCG1; FCGR1; IGFR1; FCGR1A Location Cell membrane Accession P12314 Clone Number S 2866 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance

Product Specification


Host Mouse
Antigen FcεRIα
Synonyms High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI (FcRI); Fc-gamma RIA (FcgammaRIa); CD64; FCG1; FCGR1; IGFR1; FCGR1A
Location Cell membrane
Accession P12314
Clone Number S-2866
Antibody Type Mouse mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:400 Hu

Background

FcεRIα is a single-pass transmembrane glycoprotein of the immunoglobulin superfamily that forms the ligand-binding backbone of the tetrameric high-affinity IgE receptor (FcεRI) expressed on mast cells and basophils; its extracellular region folds into two Ig-like domains that clamp the Fc portion of IgE with picomolar affinity, positioning the constant heavy-chain ε2-3 interface for optimal recognition, while a short cytoplasmic tail lacks signaling motifs but critically nucleates the entire receptor complex by juxtamembrane interactions with the four-helix FcεRIβ subunit and the disulfide-linked FcRγ homodimer, thereby dictating the architecture of the transmembrane three-helix bundle that propagates ITAM-based phosphorylation cascades upon IgE/allergen crosslinking and drives immediate degranulation, cytokine release and the clinical manifestations of type I hypersensitivity.

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SKU: 71674245702

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4.1 ★★★★★
Based on 30 reviews
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R
Verified Purchase
Renegade Rebel
San Leandro, US
★★★★★ 5
Made in America nano-hydroxyapatite Toothpaste that's Well Worth Buying.
Size: 4 Ounce (Pack of 3), Set name: E. Orange Cream, Watermelon Mint, Strawberry Mango
This review is pretty much the same as the one I wrote for the Boka Coco Ginger. Boka Toothpaste is just that good. I've been using the Japanese brand Apagard Premio toothpaste for a couple of years now and recently I noticed this Boka toothpaste while looking for alternatives that wold be less costly. I've been using this toothpaste since the end of May, 2025. I wish they would sell it in larger tubes. Boka Toothpaste is very mild and makes brushing your teeth better. It doesn't have that harsh mint flavor which with most toothpastes feels like it's burning your mouth. It comes in multiple flavors and when you're done brushing your teeth, there is no need to rinse your mouth as it is a safe toothpaste to use. After having used it for a few days, I decided that I will keep using the Boka brand from now on. I just wish that most stores would carry this toothpaste instead pf selling all those major brands which are full of fluoride. Did a bit of research and found that Boka Toothpaste has the same percentage of nano-hydroxyapatite as Apagard Premio which is 10%. So that means that Boka Toothpaste is just as good if not better. No Fluoride No Harsh burning Mint Flavor Safe to shallow Multiple flavors 10% nano-hydroxyapatite Keeps your teeth Strong And one thing I've noticed is nano-hydroxyapatite makes your teeth less sensitive by rebuilding your tooth enamel I ordered four flavors, Watermelon Mint, Strawberry Mango, Orange Cream and Coco Ginger. So far, I've tried the Coco Ginger and I was surprised at how mild it was and it didn't have the sharp taste that ginger usually has. It is good and I enjoy it. I also tried the Orange Cream which was good. I'm looking forward to trying the other flavors. The Orange Cream I'm sure my wife will like if I can get her to try it. But she can be very stubborn at times. I see there are some other flavors which I intend to try such as the Cinnamint, Cucumber Dill, Lemon Lavender and Strawberry Basil. Not sure if I should try the Ela Mint as I don't know how strong or mild the mint will be. I'm sure that if places such as Walmart brick & mortar stores sold this toothpaste, that it would sell really well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 24, 2025
V
Verified Purchase
Victoria H.
Carnegie, US
★★★★★ 5
Favorite toddler toothpaste
Size: 4 Ounce (Pack of 1), Set name: A. Strawberry Mango
I bought this for my 18month old who has all his teeth already. It works great. The smell is pleasant, the taste isn’t harsh, and the texture isn’t as thick as most toothpastes - perfect for a toddler. I’ve been using this for a couple of months now and have not noticed any irritation. He enjoys it about as much as any 18 month will, ha! It’s just as effective as fluorinated toothpaste. You get what you pay for. It’s a big tube!
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Reviewed in the United States on May 18, 2026
N
Verified Purchase
N J
West Palm Beach, US
★★★★★ 4
Good flavor, not as full of tubes as I expected.
Size: 4 Ounce (Pack of 2), Set name: G. Orange Cream, Ela Mint
My kids have LOVED brushing their teeth with this. They had been fighting to let us brush for a while, so it was nice to find something they liked. My husband and I have been using the mint flavor, and it’s been good as well. We like the ingredients, and the texture is nice. The tubes both felt like they could have fit more, so I took off a star for size/value.
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Reviewed in the United States on March 9, 2026
M
Verified Purchase
Meghan
Massapequa, US
★★★★★ 5
Very effective!
Size: 4 Ounce (Pack of 1), Set name: A. Strawberry Mango
I switched my son to this toothpaste and it has been great! I haven’t noticed whitening, but his teeth do look good and clean after he has brushed. He loves the flavor. And he is one to complain about “spicy” toothpaste. This toothpaste has never been whined about in my household. In fact, switching to this toothpaste has made brushing his teeth simpler because he enjoys the flavor so much. I have noticed it doesn’t foam up like other toothpaste’s do. Another side story, and probably the biggest thing, I think this is actually shrinking my sons cavities. His pediatric dentist told me he would need fillings before his teeth could fall out at 12 (12 year molars). I saw the cavities on the xrays. A year later, the cavities are smaller. And the dentist said if things can maintain this way, there will be no need for fillings! He does brush morning and night, and often after lunch because we homeschool and he has that ability. But I’m just thrilled that my son could potentially avoid this procedure!
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Reviewed in the United States on April 23, 2026
K
Verified Purchase
Kiona K
Dallas, US
★★★★★ 5
Love this stuff! Both toddler and mom approved
Size: 4 Ounce (Pack of 1), Set name: A. Strawberry Mango
I'm a repeat buyer! My toddler loves the taste and I love the ingredients. Boka is an awesome brand and I feel safe giving it to my kids and knowing their teeth are being cleaned.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 18, 2026

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