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Description
LAMP1 Recombinant Rabbit mAb (SDT-405-39)Product Specification Host Rabbit Antigen LAMP1 Synonyms Lysosome associated membrane glycoprotein 1, CD107 antigen like family member A, CD107a Immunogen Recombinant Protein Accession P11279 Clone Number SDT 405 39 Antibody Type Recombinant mAb Application WB, IHC P, ICC, FC, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin
Product Specification
| Host | Rabbit |
| Antigen | LAMP1 |
| Synonyms | Lysosome-associated membrane glycoprotein 1, CD107 antigen-like family member A, CD107a |
| Immunogen | Recombinant Protein |
| Accession | P11279 |
| Clone Number | SDT-405-39 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, FC, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied. |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| ICC | 1:100 | null |
| IP | 1:50 | null |
| IHC-P | 1:500 | null |
| FC | 1:500 | null |
Background
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The LAMP-1 glycoprotein is a type I transmembrane protein [PMID: 16973206] which is expressed at high or medium levels in at least 76 different normal tissue cell types. It resides primarily across lysosomal membranes [PMID: 2584229], and functions to provide selectins with carbohydrate ligands. LAMP-1 has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells, and may also play a role in tumor cell differentiation and metastasis.
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